Risk Factors for Follow-Up Interruption of Hiv Patients in French Guiana

Nacher, Mathieu; Guedj, Myriam El; Vaz, Tânia; Nasser, Valéry; Randrianjohany, Andry; Alvarez, Fernand; Sobesky, M.; Magnien, Christian; Couppié, Pierre

doi:10.4269/ajtmh.2006.74.915

Cited by 39 publications

(28 citation statements)

References 2 publications

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“…This is consistent with studies showing that HIV-infected men are less likely to access treatment [22], [23], present with more advanced stages of HIV disease [24] and have a higher mortality risk during ART [25], [26], [27], [28], [29], [30], [31], [32]. Repeated CD4 counts were less likely in individuals under 30 years of age as also reported elsewhere[33].…”

Section: Discussionsupporting

confidence: 91%

Linkage to HIV Care and Antiretroviral Therapy in Cape Town, South Africa

et al. 2010

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BackgroundAntiretroviral therapy (ART) has been scaled-up rapidly in Africa. Programme reports typically focus on loss to follow-up and mortality among patients receiving ART. However, little is known about linkage and retention in care of individuals prior to starting ART.MethodologyData on adult residents from a periurban community in Cape Town were collected at a primary care clinic and hospital. HIV testing registers, CD4 count results provided by the National Health Laboratory System and ART registers were linked. A random sample (n = 885) was drawn from adults testing HIV positive through antenatal care, sexual transmitted disease and voluntary testing and counseling services between January 2004 and March 2009. All adults (n = 103) testing HIV positive through TB services during the same time period were also included in the study. Linkage to HIV care was defined as attending for a CD4 count measurement within 6 months of HIV diagnosis. Linkage to ART care was defined as initiating ART within 6 months of HIV diagnosis in individuals with a CD4 count ≤200 cells/µl taken within 6 months of HIV diagnosis.FindingsOnly 62.6% of individuals attended for a CD4 count measurement within 6 months of testing HIV positive. Individuals testing through sexually transmitted infection services had the best (84.1%) and individuals testing on their own initiative (53.5%) the worst linkage to HIV care. One third of individuals with timely CD4 counts were eligible for ART and 66.7% of those were successfully linked to ART care. Linkage to ART care was highest among antenatal care clients. Among individuals not yet eligible for ART only 46.3% had a repeat CD4 count. Linkage to HIV care improved in patients tested in more recent calendar period.ConclusionLinkage to HIV and ART care was low in this poor peri-urban community despite free services available within close proximity. More efforts are needed to link VCT scale-up to subsequent care.

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Section: Discussionsupporting

confidence: 91%

Linkage to HIV Care and Antiretroviral Therapy in Cape Town, South Africa

et al. 2010

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“…Conversely, those who do not have regular hospital visits are associated with a high risk of self‐interruption, resulting in treatment failure . It has also been shown that younger age is a risk factor for unsuccessful clinical outcomes among HIV patients . Our study found that young patients usually visited the hospital with symptoms such as epigastralgia.…”

Section: Discussionmentioning

confidence: 58%

Clinical background factors affecting outcomes of Helicobacter pylori eradication therapy in primary care

Yokota

Amenomori

et al. 2019

J of Gen and Family Med

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Objective Few studies have reported the influence of clinical background factors on the outcome of Helicobacter pylori eradication therapy in primary care practice. We aimed to determine which clinical background factors influence the outcome of eradication therapy in a primary care setting. Methods This was a retrospective study of patients who received H pylori eradication therapy at Higashiohmi City Gamo Medical Center, Shiga, Japan, from January 2012 to December 2015. We investigated clinical background factors associated with success, failure, and self‐interruption of H pylori eradication therapy: patients’ age, gender, first‐ or second‐line treatment, reasons for receiving gastroenterological endoscopic examination, method of drug administration, and attending physicians’ age and their specialties. Results There were 369 patients (208 females, 161 male), with a mean age of 59 years (range 30‐88 years). The middle‐aged group (50‐69 years) was associated with successful eradication therapy compared with the young group (30‐49 years). The elderly group (>70 years) was associated with eradication therapy failure compared with the middle‐aged group. The young group was associated with self‐interruption of eradication therapy. There was a marginally significant association between male patients and self‐interruption. Older attending physicians (>50 years) were also associated with failure compared with younger physicians. There was no difference in outcome of eradication therapy between generalists and gastroenterology specialists. Conclusion We have identified clinical factors associated with success, failure, and self‐interruption of H pylori eradication therapy in a primary care setting.

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“…This article provides information on the constitution of the cohort and the efforts made to ensure the quality of the database, as well as the characteristics of the patients with active follow-up. Scientific studies have already been performed on this cohort [13][14][15][16][17][18][19][20][21] and several are under analysis. As a consequence of the methods of data capture and quality control, scientific analyses are possible with very short time delay.…”

Section: Discussionmentioning

confidence: 99%

A large French prospective cohort of HIV‐infected patients: the Nadis Cohort

et al. 2009

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The aim of this article is to describe the development of a dynamic French cohort of HIV-infected patients, the methodological issues and decisions made, and the characteristics of the patients currently enrolled. MethodsData are collected during medical encounters. Data quality is ensured by automated checks during data capture, by regular controls, by annual assessments, and by ad hoc processes before any scientific analysis is performed. ResultsIn September 2007, 10 458 patients representing 59 383 patient-years of follow-up were followed in our centres, including 446 with a first HIV diagnosis in the past year. Among these recently diagnosed patients, 25.6% presented with late diagnosis. Our cohort included 3017 women (28.8%). The women were less likely to be receiving highly active antiretroviral therapy (HAART) than men, and when treated were less likely to be receiving nonnucleoside reverse transcriptase inhibitor (NNRTI)-based regimens. Our network includes medical centres in overseas territories (1105 patients living overseas). In this particular population, women represented 38.5% of the patients, and the probable route of infection was heterosexual in 75.7% of the patients. Despite epidemiological and social disparities, more patients had nondetectable viral loads when receiving HAART in overseas departments than in metropolitan France. ConclusionThe Nadis Cohort represents a collaboration of major French HIV treatment centres. In September 2007, the cohort database contained up-to-date information on more than 10 000 patients, of whom a significant proportion were women. As a consequence of the choices made when building the cohort and the efforts made to ensure the quality of the database, scientific studies are regularly performed using this cohort.

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Risk Factors for Follow-Up Interruption of Hiv Patients in French Guiana

Cited by 39 publications

References 2 publications

Linkage to HIV Care and Antiretroviral Therapy in Cape Town, South Africa

Linkage to HIV Care and Antiretroviral Therapy in Cape Town, South Africa

Clinical background factors affecting outcomes of Helicobacter pylori eradication therapy in primary care

A large French prospective cohort of HIV‐infected patients: the Nadis Cohort

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