Risk factors for epilepsy in children with cerebral palsy

Epilepsy and cerebral palsy: Characteristics and trends in children born in 1976–1998

“…This is similar to reports from other studies, where children with hemiplegia (US-CP) were more at risk than those with diplegia (BS-CP able to walk). 9,13 This clinical finding reflects findings from imaging studies that show that deep grey matter lesions are more often seen in US-CP than in BS-CP. 29 Further, children with hemiplegia, those with perinatal arterial ischemic stroke seemed more at risk for epilepsy with a rate reaching 54% in a recent study.…”

“…In order to improve precision, this group can be subdivided, based on walking ability, as walking ability is less prone to coding variability between registers. In other studies, 1,3,13,28 children with spastic tetraplegia are those more at risk for epilepsy. In our study, we found that BS-CP children unable to walk (likely to be similar to tetraplegic CP) were much more likely to suffer from epilepsy than those able to walk (similar to diplegic CP with predominantly periventricular white matter lesion).…”

“…Kulak et al 9 showed that low birth weight was associated with increased risk of epilepsy whereas gestational age had no impact. Conversely, Zelnik et al 13 reported that children born at term were at increased risk. Our results corroborate this last study as we found a OR of two of developing epilepsy for children born at term or !2500 g when compared with children born extremely preterm or of very low birthweight.…”

“…22 The frequency of epilepsy in children with CP reported here is consistent with studies performed in other settings. 9,11,13 However, lower rates are reported when the definition is more restricted; e.g. seizures in the last 12 months were observed in 17% of children with CP in a population-based Canadian study.…”

The Polypeptide Stimulator Application in Complex Treatment of Cognitive Disorders in Children With Diseases of the Central Nervous System

“…Одной из актуальных проблем неврологии является эпилепсия, которая нередко протекает на фоне задерж-ки психомоторного развития, нарушения когнитивных функций, когда наряду с базовой антиконвульсантной терапией присутствует необходимость назначения препа-рата, обладающего церебропротективным и нейротроп-ным действием, а также не вызывающего повышения судорожной активности [28][29][30][31][32][33].…”