Risk Factors for Complications After Congenital Cataract Surgery without Intraocular Lens Implantation in the First 18 Months of Life

Kuhli-Hattenbach, Claudia; Lüchtenberg, Marc; Kohnen, Thomas; Hattenbach, Lars‐Olof

doi:10.1016/j.ajo.2008.02.014

Cited by 77 publications

(44 citation statements)

References 31 publications

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“…This early intervention has to be balanced against the risk of associated problems, particularly glaucoma and anesthetic complications. 6,7 Birch and Stager 8 found that surgery performed for unilateral dense congenital cataracts before 6 weeks of age minimized the effects of unilateral visual deprivation on the developing visual system. 8 Bilateral visual deprivation appears to affect the visual system differently: the neurophysiological changes in this situation are not caused by unequal competition for cortical representation.…”

Section: Discussionmentioning

confidence: 99%

Duration of form deprivation and visual outcome in infants with bilateral congenital cataracts

Jain

Ashworth

Biswas

et al. 2010

Journal of American Association for Pediatric Ophthalmology and

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Section: Discussionmentioning

confidence: 99%

Duration of form deprivation and visual outcome in infants with bilateral congenital cataracts

Jain

Ashworth

Biswas

et al. 2010

Journal of American Association for Pediatric Ophthalmology and

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“…15,31 Ken Nischal's group have recently shown that when congenital cataract surgery is traumatic the risk of glaucoma may increase. 33 In a series of 98 eyes of 62 children who had congenital cataract surgery during the first year of life, 9.8% of aphakic eyes and 13.5% of pseudophakic eyes developed glaucoma over a mean follow-up period of 2.5 years.…”

Section: Discussionmentioning

confidence: 99%

The incidence of glaucoma following paediatric cataract surgery: a 20-year retrospective study

Tatham

Odedra

Tayebjee

et al. 2010

Eye

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Aims To analyse the incidence of glaucoma in children undergoing cataract surgery and determine whether early surgery is associated with increased risk of glaucoma. Methods A retrospective chart review of all children aged 14 years or less who had surgery for congenital or developmental cataract at one unit over the last 20 years. The children were divided into three groups; group 1 consisting of children aged p50 days at surgery, group 2 those aged 51 days to 1 year, and group 3 aged 1-14 years. Results We identified a total of 104 eyes of 74 children. The medical records for 100 eyes (71 children) were available for review. In all, 17 eyes (12 children) were aged p50 days at surgery, none of which have developed glaucoma. Group 2 consisted of 28 eyes (17 children) with one patient developing glaucoma in both eyes 11 years after surgery. Group 3 consisted of 55 eyes (42 children), none of which have developed glaucoma. After a median follow-up period of 4.9 years (range 0.6-19.6 years, mean 6.4 ± 5.2 years) 2% of eyes had developed glaucoma. There was no significant difference in the length of follow-up between groups (H ¼ 2.979, P ¼ 0.22, Kruskal-Wallis Test). Conclusions There was a low incidence of glaucoma in our series and this was not increased in those having surgery in the first 6 weeks of life. Our findings contribute further evidence for the variability in prevalence of glaucoma after paediatric cataract extraction in the literature and suggest that factors other than age at surgery are important risk factors for this condition.

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“…[1][2][3][4][5][6][7][8][9][10][11][12][13] Oranlar arasındaki bu farklılık çalışmaya dahil edilen hasta gruplarının yaş ve takip sürelerinin farklı olmasına, tanı kriterlerine, katarakt dışı oküler ve sistemik anomalili hastaların çalışmaya dahil edilip edilmemesine ve cerrahi teknik farklılıklarına bağlı olabilmektedir. Ayrıca hastaların genellikle asemptomatik oluşu, göz içi basıncının ölçümü ve diğer muayenelerdeki zorluklar tanı koymayı güçleştirmektedir.…”

Section: Discussionunclassified

“…İnsidans, olguların özelliklerine ve takip süresinin uzunluğuna bağlı olarak %2 ile %58,7 arasında değişen oranlarda bildirilmektedir. [1][2][3][4][5][6][7][8][9][10][11][12][13] Konjenital kataraktlı olguların sadece ameliyat edilmiş gözlerinde ortaya çıkması, 2,14 glokom gelişimi için cerrahinin şart olduğunu göstermektedir. Cerrahinin trabeküler ağ üzerine etkilerini açıklamaya yönelik çeşitli teoriler 12,15 bulunmakla birlikte patogenez tam olarak bilinmemektedir.…”

Section: Gi Riflunclassified

“…1,2 Literatürde risk faktörlerini araştıran çok sayıda çalışma bulunmaktadır. [1][2][3][4][5][6][10][11][12][13] Çalışmaların ortak noktası erken cerrahinin en önemli risk faktörü olduğu yönündedir. [1][2][3][4][5][6][10][11][12][13] Diğer risk faktörleri olarak ise mikrokornea, 2,3,13,16 mikroftalmi, 17 kataraktın tipi (nükleer katarakt), 6,13,16 persistan hiperplastik primer vitreus (PHPV), 2 ailede glokom öyküsü, 2,6 primer arka kapsülotomi ve ön vitrektomi, 2,3,12 postoperatif üveit ve membran cerrahisi 3 bildirilmektedir.…”

Section: Gi Riflunclassified

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Konjenital Katarakt Cerrahisi Sonrası Sekonder Glokom ve Risk Faktörleri

Solmaz¹,

Önder²,

Koca³

2011

tjo

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Girifl: Konjenital katarakt nedeniyle opere edilen hastalarımızda, glokom insidansını ve risk faktörlerini belirlemek. Yöntem ve Gereç: Ocak 2001-Aralık 2009 tarihleri arasında kliniğimizde ameliyat edilen konjenital kataraktlı olguların verileri retrospektif olarak değerlendirildi. Glokom gelişiminde potansiyel risk faktörleri olarak; primer cerrahi sırasındaki yaş, mikrokornea, eşlik eden sistemik patoloji varlığı ve afaki/psödofaki parametreleri analiz edildi. En az 6 aylık postoperatif takibi bulunan 37 olgunun 65 gözü çalışma kapsamına alındı. Sonuçlar: Olguların primer cerrahi sırasındaki yaş ortalaması 35,6±43,9 (2 ay-17 yıl) aydı. Ortalama 38,6±28,1 (6 ay-8,5 yıl) aylık takip sürecinde 8 olgunun 14 gözünde (%21,5) sekonder glokom geliştiği gözlendi. Cerrahi ile glokom tanısı arasındaki interval 20 ay ile 7 yıl arasında değişmekteydi (47,3±23,3 ay). Afakik ve psödofakik gözler arasında glokom insidansı yönünden fark yoktu. Cerrahi yaşı (p<0,001), mikrokornea (p=0,001) ve sistemik patoloji varlığının(p=0,07) ise glokom gelişimi ile güçlü bir ilişkisi olduğu saptandı. Glokomlu olguların primer cerrahi yaşı ortalama 7.4 ay olup glokom gelişmeyen gruptan (43,4 ay) anlamlı derecede daha düşük, takip süresi ise daha uzundu (p=0,003). Mikrokornealı gözlerde %60, sistemik patolojili olgularda ise %38,5 glokom görülürken, bu oranlar kornea çapı normal olan gözlerde %14,5 ve sistemik sorunu olmayanlarda %10,3'e düşmekteydi. Tart›flma: Erken yaşta cerrahi, mikrokornea ve sistemik patolojilerin varlığı önemli risk faktörleri olup; takip süresi uzadıkça glokom insidansı artmaktadır. Glokomatöz hasara bağlı görme kaybını engellemek için bu hastalar yaşam boyu takip edilmelidir. ( Sum maryPur po se: To determine the risk factors and incidence of glaucoma following congenital cataract surgery in our case series. Patients and Methods: Records of children who underwent cataract surgery between January 2001 and December 2009 were reviewed retrospectively. Age at primary surgery, microcornea, aphakia/ pseudophakia and associated systemic pathology were analyzed as potential risk factors for glaucoma secondary to surgery. Sixty-five eyes of 37 patients having a minimum 6-month follow-up were included in the study. Results: Age at surgery was 35.6±43.9 months (2 months-17 years) with a follow-up period of 38.6±28.1 months (6 months-8.5 years). Glaucoma developed in 8 patients (14 eyes; 21.5%). Time between surgery and glaucoma diagnosis was 47.3±23.3 months (20 months-7 years). Glaucoma incidence in aphakic and pseudophakic cases did not differ. Glaucoma development significantly correlated with age at surgery (p<0.001), microcornea (p=0.001) and presence of systemic pathology (p=0.007). Mean age at surgery was significantly lower in patients with glaucoma diagnosis (7.4 months) than in those who did not develop glaucoma (43.4 months). However, the mean follow-up period was significantly longer in patients with glaucoma (p=0.003). Whereas glaucoma developed in 60% and 38.5% of the eyes of patients with microcornea and systemi...

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Risk Factors for Complications After Congenital Cataract Surgery without Intraocular Lens Implantation in the First 18 Months of Life

Cited by 77 publications

References 31 publications

Duration of form deprivation and visual outcome in infants with bilateral congenital cataracts

Duration of form deprivation and visual outcome in infants with bilateral congenital cataracts

The incidence of glaucoma following paediatric cataract surgery: a 20-year retrospective study

Konjenital Katarakt Cerrahisi Sonrası Sekonder Glokom ve Risk Faktörleri

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