“…In addition, whether levofloxacin performs equally or better in a sequential regimen has not been evaluated. In China, the primary resistance rates to levofloxacin in H. pylori range from 0 to 41.7%, which are lower than that for metronidazole and clarithromycin [12,[27][28][29][30][31][32][33][34][35][36][37]. Therefore, the present multicenter, randomized and controlled study was designed and conducted to compare the eradication rates as well as the adverse effects of a levofloxacin-containing triple therapy, and a modified levofloxacin-containing sequential therapy, in comparison with the standard sequential therapy.…”