Risk factors associated with extended spectrum beta-lactamase Escherichia coli (CTX-M) on dairy farms in North West England and North Wales

Snow, L. C.; Warner, RG; Cheney, Tanya; Wearing, Heather; Stokes, M. O.; Harris, Kate; Teale, Christopher; Coldham, N. G.

doi:10.1016/j.prevetmed.2012.03.009

Cited by 96 publications

(96 citation statements)

References 26 publications

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“…Relative to risk factors associated with the presence of ESBL-producing Enterobacteriaceae, the risk factors found in our study differ from those reported in previous studies in England and north of Wales, Switzerland and Israel (Snow et al, 2012;Reist et al, 2013;Adler et al, 2015) considering that independent variables are different between studies. In these studies, the following factors: use of third and fourth generation cephalosporins in the last 12 months, operating as an open farm, infrequent cleaning of equipment for feeding of calves and storage of fecal matter in manure tanks, animals originating from farms with primary production type dairy, animals originating from farms with more than one animal movement per day per 100, lack of a cooling system, increased crowdedness and lack of manure cleaning, antimicrobial prophylaxis and increased frequency of veterinarian visits, were associated with the presence of ESBL-producing Enterobacteriaceae in cattle (Snow et al, 2012;Reist et al, 2013;Adler et al, 2015).…”

Section: Discussioncontrasting

confidence: 99%

“…In these studies, the following factors: use of third and fourth generation cephalosporins in the last 12 months, operating as an open farm, infrequent cleaning of equipment for feeding of calves and storage of fecal matter in manure tanks, animals originating from farms with primary production type dairy, animals originating from farms with more than one animal movement per day per 100, lack of a cooling system, increased crowdedness and lack of manure cleaning, antimicrobial prophylaxis and increased frequency of veterinarian visits, were associated with the presence of ESBL-producing Enterobacteriaceae in cattle (Snow et al, 2012;Reist et al, 2013;Adler et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

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Presencia de Enterobacteriaceae productoras de betalactamasa de espectro extendido (ESBL) en leche de tanque a granel de granjas lecheras bovinas en Antioquia, Colombia

Vásquez-Jaramillo

Ramı́rez

Akineden

et al. 2017

Rev Colomb Cienc Pecu

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Presencia de Enterobacteriaceae productoras de betalactamasa de espectro extendido (ESBL) en leche de tanque a granel de granjas lecheras bovinas en Antioquia, Colombia

Vásquez-Jaramillo

Ramı́rez

Akineden

et al. 2017

Rev Colomb Cienc Pecu

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“…As it has been highlighted by various authors, ESBLs mediate resistance to the thirdgeneration cephalosporins (Paterson and Bonomo, 2005;Ogbolu et al, 2011;Snow et al, 2012). The antimicrobial susceptibility pattern of ESBLproducing organisms in the hereby study was congruent with the fact as the cephalosporins-ceftazidime, cefixime and cefuroxime showed poor efficacy against these organisms in vitro.…”

Section: Detection Of Extended Spectrum Beta Lactamasesupporting

confidence: 83%

Detection of Extended Spectrum Beta-Lactamases Among Gram Negative Bacilli Recovered from Cattle Feces In Benin City, Nigeria

Ogefere¹,

Agbe²,

Ibadin³

2017

Not Sci Biol

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This study was carried out to determine the prevalence of extended spectrum beta-lactamase (ESBL) among Gram negative bacteria isolated from cattle feces in Benin City, Nigeria. A total of 250 Gram negative bacteria isolates were recovered from cattle feces and were processed microbiologically using standard techniques. Emergent colonies were identified and antibacterial susceptibility tests were determined using Kirby-Bauer disk diffusion method. All bacterial isolates were screened for the presence of ESBL using the double-disc synergy method. A total of 37 (14.8%) isolates were positive for ESBL, with 33 (13.2%) indicated by ceftazidime, while only 4 (1.6%) were indicated by both ceftazidime and cefotaxime (P < 0.0001). Of the Gram negative bacterial isolates recovered, Salmonella species was the most prevalent ESBL-producer with 55.0% prevalence (P = 0.0092), while no isolate of Pseudomonas aeruginosa produced ESBL. ESBL-positive isolates showed poor susceptibility to the tested antibacterial agents in comparison with non-ESBL-producers and imipenem was the most active antibiotic. The prevalence of ESBL among Gram negative bacilli recovered from cattle feces was 14.8%. The study advises prudent use of antibiotics in the treatment of cattle and harps on improved hygiene in managing cattle, as they are potential reservoirs of ESBL-producing organisms.

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“…A study of 65 dairy farms in the United Kingdom found a significant association between the use of a third-or fourth-generation cephalosporin in the previous 12 months and the presence of CTX-M E. coli on the farm (46). Therefore, an expanded Washington State study in which cephalosporin use is specifically targeted will be required to address this question locally.…”

Section: Fig 2 Prevalence Of Samples That Yielded E Coli Isolates Pomentioning

confidence: 99%

Recent Emergence of Escherichia coli with Cephalosporin Resistance Conferred by bla _CTX-M on Washington State Dairy Farms

Davis

Sischo

Jones

et al. 2015

Appl Environ Microbiol

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c Enterobacteriaceae-associated bla CTX-M genes have become globally widespread within the past 30 years. Among isolates from Washington State cattle, Escherichia coli strains carrying bla CTX-M (CTX-M E. coli strains) were absent from a set of 2008 isolates but present in a set of isolates from 2011. On 30 Washington State dairy farms sampled in 2012, CTX-M E. coli prevalence was significantly higher on eastern than on northwestern Washington farms, on farms with more than 3,000 adult cows, and on farms that recently received new animals. The addition of fresh bedding to calf hutches at least weekly and use of residual fly sprays were associated with lower prevalence of CTX-M E. coli. In Washington State, the occurrence of human pathogens carrying bla CTX-M genes preceded the emergence of bla CTX-M -associated E. coli in cattle, indicating that these resistance determinants and/or their bacterial hosts may have emerged in human populations prior to their dissemination to cattle populations. E mergence and dissemination of antibiotic resistance traits in Gram-negative bacteria can occur rapidly and across wide geographic distances (1). Bacterial strains carrying the bla CTX-M family of extended-spectrum ␤-lactamase (ESBL) genes have spread globally in less than 30 years (2, 3). Unlike other families of ESBL genes which result from point mutations in preexisting, narrower-spectrum ␤-lactamase genes (bla TEM-1 and bla SHV ) (4), bla CTX-M ␤-lactamase genes originated from chromosomal genes of Kluyvera species (2). The earliest Escherichia coli plasmid-associated bla CTX-M was detected from laboratory dogs used in pharmaceutical research in Japan in 1986, followed by isolations from human patients in Munich, Germany (1989), Argentina (1989), France (1989), and Poland (1996) (2). In North America, bla CTX-Mbearing Escherichia coli strains (CTX-M E. coli strains) were detected in humans in Canada in 2000 (5) and in the United States between 2001 and 2002 (6). By 2007 in the United States, 80% of 15 geographically dispersed medical centers reported E. coli or Klebsiella pneumoniae infections with associated bla CTX-M genes (7). In Washington State, the earliest reported clinical human E. coli strain carrying bla CTX-M was isolated in 2001 in Seattle (6). Currently, CTX-M enzymes are considered the most prevalent ESBLs in isolates of E. coli, K. pneumoniae, and Proteus mirabilis associated with human infections globally (8).In the United States, dairy cattle-associated CTX-M E. coli strains were first reported by Wittum and others in Ohio in 2009 (9). This Ohio research group later reported CTX-M in Salmonella enterica isolates from equine, swine, and turkey sources from six different states (10) and from swine finishing barns in 5 states (11). In the current study, we first tested E. coli isolates from Washington State dairy cattle banked from several earlier research projects to determine the time window of CTX-M E. coli emergence in this region and host species. The results of this retrospective study indicated rece...

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Risk factors associated with extended spectrum beta-lactamase Escherichia coli (CTX-M) on dairy farms in North West England and North Wales

Cited by 96 publications

References 26 publications

Presencia de Enterobacteriaceae productoras de betalactamasa de espectro extendido (ESBL) en leche de tanque a granel de granjas lecheras bovinas en Antioquia, Colombia

Presencia de Enterobacteriaceae productoras de betalactamasa de espectro extendido (ESBL) en leche de tanque a granel de granjas lecheras bovinas en Antioquia, Colombia

Detection of Extended Spectrum Beta-Lactamases Among Gram Negative Bacilli Recovered from Cattle Feces In Benin City, Nigeria

Recent Emergence of Escherichia coli with Cephalosporin Resistance Conferred by bla _CTX-M on Washington State Dairy Farms

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Risk factors associated with extended spectrum beta-lactamase Escherichia coli (CTX-M) on dairy farms in North West England and North Wales

Cited by 96 publications

References 26 publications

Presencia de Enterobacteriaceae productoras de betalactamasa de espectro extendido (ESBL) en leche de tanque a granel de granjas lecheras bovinas en Antioquia, Colombia

Presencia de Enterobacteriaceae productoras de betalactamasa de espectro extendido (ESBL) en leche de tanque a granel de granjas lecheras bovinas en Antioquia, Colombia

Detection of Extended Spectrum Beta-Lactamases Among Gram Negative Bacilli Recovered from Cattle Feces In Benin City, Nigeria

Recent Emergence of Escherichia coli with Cephalosporin Resistance Conferred by bla CTX-M on Washington State Dairy Farms

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Recent Emergence of Escherichia coli with Cephalosporin Resistance Conferred by bla _CTX-M on Washington State Dairy Farms