Risk Factor for Mortality in COVID-19 Patients in Mohammad Hoesin Hospital, Palembang, Indonesia

Sitorus, Rico Januar; Antara, Nyoman Yudi; Elviani, Rosyada; Ahmad, Zen; Hudari, Harun; Sangalang, Reymart V.

doi:10.26553/jikm.2021.12.1.69-76

Cited by 3 publications

(2 citation statements)

References 14 publications

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“…So this needs special attention because comorbid hypertension is also a risk factor for other diseases such as cardiovascular, stroke, and kidney failure. Likewise with Sitorus (2021), the results showed that COVID-19 patients who died in hospital had symptoms of dyspnea and had a history of contact with confirmed COVID-19 positive patients. Patients who have comorbidities have a greater risk of death than patients who do not have comorbidities.…”

Section: Funnel Plotmentioning

confidence: 65%

A Meta-Analysis: Correlation between Hypertension of Comorbidity on Mortality in Patients with COVID-19

Simatupang¹,

Widyaningsih²,

Sumardiyono³

2021

J EPIDEMIOL PUBLIC HEALTH

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Background: SARS-CoV-2 is a new type of coronavirus that has never been previously identified in humans. In severe cases of COVID-19 it can cause pneumonia, acute respiratory syndrome, kidney failure, and even death. Hypertension causes a number of pathophysiological changes in the cardiovascular system such as left ventricular hypertrophy and fibrosis. This can make a hypertensive heart particularly vulnerable to SARS-CoV-2. This study aims to analyze and estimate the effect of comorbid hypertension on mortality in COVID-19 patients. Subjects and Method: This was a systematic review and meta-analysis conducted with PRISMA flow diagram. Article searches through journal databases include: Google Scholar, PubMed, Science Direct, and Springer Link by selecting articles published in 2020 and 2021. The keywords used are "Hypertension" OR "Hypertensive Patient" OR "Blood Pressure", "Systolic Pressure" OR "Diastolic Pressure" AND "Mortality", OR "death" OR "loss" AND "COVID-19" OR "SARS-COV-2" OR "coronavirus" AND "multivariate". The inclusion criteria were full paper articles with observational research methods, the results of the analysis used the aOR value, the exposure given was comorbid hypertension, the research subjects were COVID-19 patients, with mortality outcomes. Eligible articles were analyzed using the Revman 5.3 app. Results: A meta-analysis of 18 articles showed that confirmed COVID-19 patients who had comorbid hypertension had a 1.27 times risk of mortality compared to those without comorbid hypertension and were statistically significant (aOR= 1.27; 95% CI= 1.14 to 1.41; p <0.001). Conclusion:Comorbid Hypertension affects the mortality of COVID-19 patients.

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Section: Funnel Plotmentioning

confidence: 65%

A Meta-Analysis: Correlation between Hypertension of Comorbidity on Mortality in Patients with COVID-19

Simatupang¹,

Widyaningsih²,

Sumardiyono³

2021

J EPIDEMIOL PUBLIC HEALTH

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“…The Covid-19 pandemic has had various negative consequences on all corners [10]. The Covid-19 virus is also the cause of the highest death rate [9,11]. Maintaining distance, also known as social distancing, limits selection to prevent the covid-19 virus from spreading [12].…”

Section: Introductionmentioning

confidence: 99%

Untitled

2022

J. Med. Chem. Sci.

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Blood Gas Analysis as A Predictor of Mortality in Critical COVID-19 Patients in Dr. Moewardi Hospital Surakarta

Cahyaningrum

Ariningrum

Primaningtyas

et al. 2023

Indonesian J. Clin. Pathol. Med. Lab.

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COVID-19 has been declared a global pandemic affecting many countries, including Indonesia. The worsening of COVID-19 patients may go unnoticed because one of the clinical manifestations of COVID-19 is silent hypoxia, where the patients’ blood oxygen saturation drops with no visible symptoms. Blood gas analysis is needed to detect silent hypoxia. This study aims to confirm whether blood gas analysis results correlate with the mortality of critical COVID-19 patients. This was a retrospective cohort study, the samples were taken from the medical records of critical COVID-19 patients from May 2020-July 2021. The variables observed were gender, age, comorbidities, oxygen saturation (SaO2), partial pressure of oxygen (PaO2), partial pressure of carbon dioxide (PaCO2), bicarbonate (HCO3-), and blood pH. Descriptive statistics, bivariate, and multivariate analyses were done. There were 210 samples, where 137 patients survived (65.24%) and 73 patients died (34.76%). The data analysis showed that comorbidities and blood pH significantly correlate with the mortality of critical COVID-19 patients, with p-values < 0.05; indicating that comorbidities and blood pH can be used as mortality predictors in critical COVID-19 patients. The RR for comorbidities and blood pH were 2.194 and 2>294, respectively, with CI 95% 1.202-4.833 for comorbidities and 1.151-5.295 for blood pH. The cut-off value used for blood pH was 7.310.

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Risk Factor for Mortality in COVID-19 Patients in Mohammad Hoesin Hospital, Palembang, Indonesia

Cited by 3 publications

References 14 publications

A Meta-Analysis: Correlation between Hypertension of Comorbidity on Mortality in Patients with COVID-19

A Meta-Analysis: Correlation between Hypertension of Comorbidity on Mortality in Patients with COVID-19

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Blood Gas Analysis as A Predictor of Mortality in Critical COVID-19 Patients in Dr. Moewardi Hospital Surakarta

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