Risk Assessment and Outpatient Management in Bleeding Peptic Ulcer

Abstract

A number of clinical and endoscopic variables (blood pressure, heart rate, and endoscopic stigmata of bleeding) with prognostic value have been identified. These are easy to obtain and apply in clinical practice and allow an accurate estimation of the evolution of UGIB. This diagnostic strategy identifies a relatively high proportion of UGIB patients who can be managed on an outpatient basis.

Acute Upper Gastrointestinal Bleeding in Central Greece: The Role of Clinical and Endoscopic Variables in Bleeding Outcome

“…Peptic ulcer remains the more common diagnosis of UGIB in almost all studies and ranges from 31 to 58%, and the diagnosis of duodenal ulcer is more common than that of gastric ulcer [1][2][3][4][5][6][7][8][9][10][11]. In the present study 57.6% of the patients had peptic ulcer disease, with a very high incidence of duodenal ulcer.…”

“…Moreover, the incidence of UGIB was not examined in the light of potential acid suppressive therapy or cyclo-oxygenase-2 selective NSAID use in either of the studies. Most prior studies estimate that the annual incidence of UGIB ranges from 36 to 172 cases per 100,000 [1][2][3]. It is possible that the incidence may be underestimated in various studies.…”

“…Advanced age, re-bleeding, and co-morbid illness are the most important risk factors for mortality. The annual incidence of UGIB worldwide varies between 36 and 172 per 100,000 adults [1][2][3]. The incidence increases markedly with age and is higher in men than in women [1][2][3].…”

“…The annual incidence of UGIB worldwide varies between 36 and 172 per 100,000 adults [1][2][3]. The incidence increases markedly with age and is higher in men than in women [1][2][3]. The risk of UGIB is elevated among non-steroidal antiinflammatory drug (NSAID), anti-coagulant drug users, and patients with organ failure [4,5].…”

Clinical Profile of Non Variceal Upper GI Bleed

“…J.Kaviani et.al were the mean age was 54.9 17 .In the study by T.C.K Tham et.al on 102 consecutive patients with non-variceal UGIB, the mean age was 59 years 18 . Gisbert et.al, in their study of 341 patients with UGIB, the mean age of patients was 62 years 19 . In the study by Cheng.…”