Right ventricular systolic echocardiographic parameters in chronic systolic heart failure and prognosis

Darahim, Khaled E.

doi:10.1016/j.ehj.2013.08.010

Cited by 4 publications

(1 citation statement)

References 26 publications

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“…Because it is preferred for feature values to be categorical, all continuous variables were disregarded before entering the decision tree algorithm. Patients were dichotomized from published predictors of mortality in PH‐LHD, including TPG ⩾̸ 12 mmHg, 10 PVR ⩾̸ 3WU 11,12 and DPG ⩾̸ 7 mmHg, 10,12 PAC < 1.1 mL/mmHg, 13 TAPSE<16 mm, peak systolic tissue Doppler velocity < 10 cm/s, 14 and right ventricular end‐diastolic area ⩾̸ 25 cm 2 9 . Less investigated and validated in PH‐LHD, cardiac index < 2.5 L/min/m 2 , right atrial pressure ⩾̸ 8 mmHg, and right atrial area ⩾̸ 18 cm 2 were also explored 15 .…”

Section: Methodsmentioning

confidence: 99%

The dangerous and contradictory prognostic significance of PVR<3WU when TAPSE<16mm in postcapillary pulmonary hypertension

et al. 2020

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Aims In 2019, pulmonary vascular resistance (PVR) < 3WU was adopted to stratify patients at low risk in pulmonary hypertension due to left heart disease (PH-LHD) as well those with isolated PH-LHD. We sought to evaluate whether supervised machine learning with decision tree analysis, which provides more information than Cox Proportional analysis by forming a hierarchy of multiple covariates, confirms this risk stratification. Methods and results Two hundred two consecutive patients (mean age: 69 ± 11 years, female: 42%) with mean pulmonary artery pressure ≥ 20 mmHg and wedge pressure > 15 mmHg were recruited. Transpulmonary pressure gradient ⩾̸ 12 mmHg, PVR ⩾̸ 3WU, diastolic pressure gradient ⩾̸ 7 mmHg, pulmonary arterial capacitance < 1.1 mL/mmHg, tricuspid annular plane systolic excursion (TAPSE) < 16 mm, peak systolic tissue Doppler velocity < 10 cm/s, right ventricular end-diastolic area ⩾̸ 25 cm 2 were the seven categorical values entered into the model due to their prognostic significance in PH. We used the chi-squared automatic interaction detection method to predict mortality. Each node and branch were compared using survival analysis at 6-year follow-up. Mean pulmonary artery pressure, wedge pressure, cardiac index, and PVR were 40.3 ± 10.0 mmHg, 22.3 ± 7.1 mmHg, 2.9 ± 0.8 L/min/m 2 , and 3.6 ± 2.1WU, respectively. Among the seven dichotomous, TAPSE was first selected following by PVR. Compared with patients with PVR < 3WU and TAPSE ⩾̸ 16 mm, patients with PVR ⩾̸ 3WU and TAPSE ⩾̸ 16 mm, or patients with PVR ⩾̸ 3WU and TAPSE<16 mm had significantly increased mortality, HR = 3.0, 95% CI = [1.4-6.4], P = 0.006 and HR = 3.3, 95% CI = [1.6-6.9], P = 0.002, respectively, while patients with PVR < 3WU and TAPSE < 16 mm exhibited the worst prognosis, HR = 7.2, 95% CI = [3.3-15.9], P = 0.0001. Conclusions Used for solving regression and classification problems, decision tree analysis confirms that PVR and TAPSE have to be analysed together in PH-LHD and revealed the dangerous and contradictory prognostic significance of PVR < 3WU when TAPSE<16 mm.

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Section: Methodsmentioning

confidence: 99%

The dangerous and contradictory prognostic significance of PVR<3WU when TAPSE<16mm in postcapillary pulmonary hypertension

et al. 2020

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Use of Cardiac Imaging to Evaluate Cardiac Function and Pulmonary Hemodynamics in Patients with Heart Failure

2019

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Morphofunctional aspects of the adaptation of foreign students to the conditions of the sharply continental climate of the Volgograd region

Sevriukova

Нефедьева

Tovmasian

et al. 2020

IOP Conf. Ser.: Earth Environ. Sci.

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The problems of monitoring of morphofunctional changes in the process of human adaptation to the changed climatic and geographic conditions of living and study are considered in the article. Various mechanisms of adaptive rearrangements of the organism are described. Changes in the morphofunctional status occur when foreign students adapt to the conditions of the sharply continental climate of the Volgograd region. Those changes cause multidirectional reactions of the cardiovascular system. A satisfactory adaptation response was found in 58.8% of cases: reduction of body weight deficit, load on the myocardium, and increase in the functional capabilities of the cardiovascular system. In a risk group of students with a deficit of body weight, in 30.0% of cases, the reserve potential of the functioning of the cardiovascular system was spent. This corresponds to maladaptation reactions. It is necessary to take into account the obtained results for organizing the measures of conserve and preserve the health of foreign students coming to Russia for higher education.

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Right ventricular systolic echocardiographic parameters in chronic systolic heart failure and prognosis

Cited by 4 publications

References 26 publications

The dangerous and contradictory prognostic significance of PVR<3WU when TAPSE<16mm in postcapillary pulmonary hypertension

The dangerous and contradictory prognostic significance of PVR<3WU when TAPSE<16mm in postcapillary pulmonary hypertension

Use of Cardiac Imaging to Evaluate Cardiac Function and Pulmonary Hemodynamics in Patients with Heart Failure

Morphofunctional aspects of the adaptation of foreign students to the conditions of the sharply continental climate of the Volgograd region

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