Right Ventricular Involvement in Hypertrophic Cardiomyopathy

Maron, Martin S.; Hauser, Thomas H.; Dubrow, Ethan; Horst, Taylor A.; Kissinger, Kraig V.; Udelson, James E.; Manning, Warren J.

doi:10.1016/j.amjcard.2007.05.061

Cited by 182 publications

(139 citation statements)

References 27 publications

Supporting

Mentioning

121

Contrasting

Unclassified

Order By: Relevance

“…These results suggest that RV size (RVIDd) and wall thickness (RVFWd), in addition to increased LV wall thickness (LVFWd), may be associated with clinical severity in cats with HCM. Furthermore, a cardiac magnetic resonance study of RV involvement in humans with HCM found a similar weak‐to‐moderate positive correlation of RV wall thickness to LV wall thickness 7. This finding can also be interpreted to suggest that the presence of RV hypertrophy (increased RVFWd) is associated with more severe disease in cats with HCM (as assessed by LV wall thickness), as suggested previously in humans8 and cats with6 HCM.…”

Section: Discussionsupporting

confidence: 78%

Echocardiographic Assessment of Right Ventricular Size and Function in Cats With Hypertrophic Cardiomyopathy

Visser

Sloan

Stern

2017

Veterinary Internal Medicne

View full text Add to dashboard Cite

BackgroundStudies evaluating right ventricular (RV) structural and functional abnormalities in feline hypertrophic cardiomyopathy (HCM) are limited.HypothesisRight ventricular structural and functional abnormalities are present in cats with HCM and are associated with clinical severity.AnimalsEighty‐one client‐owned cats.MethodsRetrospective 2‐dimensional (2D) echocardiographic study. Right atrial diameter (RAD), RV free wall thickness (RVFWd), RV internal dimension (RVIDd), RV fractional area change (FAC), and tricuspid annular plane systolic excursion (TAPSE) were measured in control cats (n = 26), cats with subclinical HCM (subclinical HCM; n = 31), and cats with HCM and congestive heart failure (HCM + CHF; n = 24).ResultsRight heart size (RAD, RVFWd, and RVIDd) and RV function (FAC and TAPSE) significantly (all P < .05) increased and decreased, respectively, in the HCM + CHF group compared with controls. In the subclinical HCM group, only RVFWd was significantly (P < .05) higher than in controls. Compared with reference intervals derived from controls, 29% of cats with HCM had increased RVFWd. Increased left ventricular free wall thickness, increased RVIDd and decreased TAPSE independently correlated with increased left atrial size. Cats with HCM and pleural effusion were significantly more likely to have increased RVFWd and had increased RAD and decreased TAPSE compared with cats without pleural effusion.Conclusions and Clinical ImportanceRight ventricular remodeling and dysfunction occur in some cats with HCM and may be associated with clinical severity. Our results support involvement of RV in the pathophysiology of HCM in some cats and support echocardiographic assessment of the RV in cats with HCM.

show abstract

Section: Discussionsupporting

confidence: 78%

Echocardiographic Assessment of Right Ventricular Size and Function in Cats With Hypertrophic Cardiomyopathy

Visser

Sloan

Stern

2017

Veterinary Internal Medicne

View full text Add to dashboard Cite

show abstract

“…75 Apical variants of HCM are also better identified by CMR. 76 CMR can show the other features of HCM such as small cavity, dynamic resting function, RV involvement, 77 outflow tract obstruction, and systolic anterior motion of the mitral valve and mitral regurgitation. The good discrimination of blood from myocardium allows accurate CMR measurements of not only wall thickness but also ventricular mass, which has been shown to be normal in 20% of patients with HCM phenotype and is a more sensitive marker of outcomes in HCM than maximal wall thickness.…”

Section: Hypertrophic Cardiomyopathymentioning

confidence: 99%

Cardiovascular Magnetic Resonance

2010

View full text Add to dashboard Cite

“…Current research demonstrates that RV wall thickening is common in this HCM population, and therefore the hypertrophic process in this disease process appears to be more diffuse than previously appreciated (7). RV hypertrophy assessed by two-dimensional echocardiography is common in patients with HCM.…”

Section: Rv Involvement In Hcmmentioning

confidence: 84%

Right ventricle myectomy

Borisov

2017

Ann. Cardiothorac. Surg.

View full text Add to dashboard Cite

Correspondence to: Konstantin V. Borisov, MD. Slavyanckaya sq., 2/5/4 b3, Moscow, 109074, Russia. Email: kvborisov@inbox.ru.Right ventricular (RV) hypertrophy is common in patients with hypertrophic cardiomyopathy (HCM), and is associated with more severe disease. Conventional surgical strategies such as the traditional Morrow procedure pose a particularly high risk to patients with severe hypertrophy and RV obstruction, for whom the most appropriate therapeutic approach has not yet been established. We have proposed a new technique for surgical correction in patients with hypertrophic obstructive cardiomyopathy and severe hypertrophy, which involves approaching the area of obstruction by entering through the conal part of the RV. This novel technique provides effective elimination of biventricular obstruction and the precise removal of the areas of septal fibrosis in patients with hypertrophic obstructive cardiomyopathy. The current literature review analyzes the indications and various techniques for performing a RV myectomy, and presents the results of follow-up assessments in patients with biventricular obstruction and severe hypertrophy.

show abstract

Right Ventricular Involvement in Hypertrophic Cardiomyopathy

Cited by 182 publications

References 27 publications

Echocardiographic Assessment of Right Ventricular Size and Function in Cats With Hypertrophic Cardiomyopathy

Echocardiographic Assessment of Right Ventricular Size and Function in Cats With Hypertrophic Cardiomyopathy

Cardiovascular Magnetic Resonance

Right ventricle myectomy

Contact Info

Product

Resources

About