Right-Sided Cardiac Tumors Detected by Transesophageal Echocardiography and Its Usefulness in Differentiating the Benign From the Malignant Ones

Lynch, Mary; Clements, Stephen D.; Shanewise, Jack S.; Chen, Cyeng C; Martin, Randolph P.

doi:10.1016/s0002-9149(96)00868-5

Cited by 48 publications

(22 citation statements)

References 3 publications

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“…The diagnostic sensitivities of transthoracic and transesophageal echocardiography are 93.3% and 96%, respectively [31]. However, cases have been described where cardiac sarcomas have eluded diagnosis by echocardiography and were eventually demonstrated by CT or by open tumour biopsy [32,33] TOE guides transvenous tumour biopsies especially with right atrial masses [34], thereby avoiding invasive diagnostic procedures [35].…”

Section: Echomentioning

confidence: 99%

Primary cardiac sarcoma

Shanmugam¹

2006

European Journal of Cardio-Thoracic Surgery

132

157

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Primary malignant lesions of the heart are rare. Although myxomas have been extensively described, there is a paucity of large studies on non-myxomatous cardiac tumours. On the other hand, there are several case reports on specific histopathological variants, in small numbers. Consequently there exists no consensus on therapeutic modalities for cardiac sarcomas. The prognosis for these lesions remains dismal, despite the enhanced diagnostic ability of newer technology. The reasons for the dismal prognosis are (1) the advanced tumour stage at presentation, (2) non-specific symptomatolgy, (3) insufficient awareness of these lesions, due to their rarity, (4) delayed diagnosis and/or misdiagnosis, which leads to (5) advanced tumour stage at presentation. Thus a vicious cycle is created. This article addresses these issues, deals with the surgically relevant modes of presentation, rather than the histopathology, and reviews the diagnosis and management options for the various sarcomas, categorized by the site and extent of cardiac involvement. Clinicians should be familiar with the presentation of these tumours and have a high index of suspicion, since the potential for long-term survival following resection does exist. Wide surgical resection remains the cornerstone of sarcoma therapy. Complete characterization of tumour extent using echocardiography and CT/MRI is mandatory to achieve this goal. Radical resections such as 'bench surgery' and transplantation may reduce local recurrence, but the risk of metastatic disease remains. The clinical experience with such approaches is limited. The role of adjuvant therapy is not yet established. In no other field of cardiac surgery would a multidisciplinary approach be more useful, in achieving cure or long-term palliation.

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Section: Echomentioning

confidence: 99%

Primary cardiac sarcoma

Shanmugam¹

2006

European Journal of Cardio-Thoracic Surgery

132

157

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“…The right chambers are the most common places of origin of the sarcomas [4]. Lynch et al [5] have shown that cardiac tumors are predominant in women, being less frequent in the ventricles and more common in the right atrium. When they begin their growth on the atrium's external side, they are usually malignant tumors.…”

Section: Discussionmentioning

confidence: 99%

Condrossarcoma mixóide de átrio direito

Cunha¹,

Santos²,

Steffen³

et al. 2008

Rev Bras Cir Cardiovasc

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We are reporting a case of a 46-year-old woman, Caucasian, with hypertension and a primary diagnosis of infectious endocarditis. A transthoracic echocardiogram was performed, suggesting right atrium myxoma. The patient was submitted to surgery, which found a tumor mass with a jelly-like exterior. The mass was sent for anatomopathological analysis, which diagnosed a myxoid chondrosarcoma tumor. After the surgical resection, the patient achieved complete recovery with no signs of recidivation after 14 months.Descriptors: Heart neoplasms. Heart atria/surgery. Chondrosarcoma. 133 CUNHA, CR ET AL -Right atrium myxoid chondrosarcomaRev Bras Cir Cardiovasc 2008; 23(1): 132-134

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“…La ocupación tumoral de las cavidades cardía-cas derechas por extensión del CHC puede estar subdiagnosticado, dada su escasa expresión clínica, siendo la ecocardiografía un examen útil en su diagnóstico y la vía transesofágica de mayor precisión para diferenciar el origen de la lesión 15,16 , como se observó en nuestros casos 2 y 3. Este examen puede, incluso, definir rápidamente el diagnóstico y la extensión intracavitaria en condiciones de urgencia, como en un caso comunicado con obstrucción de salida del ventrículo derecho durante la cirugía de un CHC con metástasis inicialmente auricular 13 .…”

Section: Discussionunclassified

Hepatocarcinoma con invasión cardiovascular: comunicación de 5 casos y revisión de la literatura

et al. 2004

Rev. méd. Chile

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The diagnosis of hepatocellular carcinoma in cirrhotic patients has increased, mainly due to early detection using newer imaging techniques. The therapeutic approach depends on the tumor staging and the liver function. Cardiac involvement has a very (Rev Méd Chile 2004; 132: 1517-22E l carcinoma hepatocelular (CHC) representa más de 5% de todos los cánceres en el mundo y las muertes relacionadas con éste se estiman en 500 mil por año 1 . Este tumor puede debutar sintomáticamente con descompensación de la cirrosis de base, o ser de sospecha en pacientes asintomáticos por estudio de imágenes o medición de alfafetoproteína (AFP). En los países desarrollados se ha visto un aumento de su incidencia en el último tiempo, probablemente relacionado con la mejoría de exámenes diagnós-ticos y por la inmigración proveniente de zonas de alta prevalencia. Por otro lado, el mejor manejo de los pacientes cirróticos y la consiguiente mayor expectativa de vida de éstos, favorece su aparición, con una sobrevida que en casos avanzados suele ser inferior a 3 meses 2,4 .El diagnóstico de CHC en pacientes cirróticos se basa actualmente en los criterios establecidos en Barcelona 3 , que consideran la presencia de al menos dos técnicas de imagen que muestren un nódulo de 2 o más centímetros con hipervascularización, o por una sola imagen asociada a AFP >400 ng/ml. Se han desarrollado varias clasificaciones para determinar el estadio tumoral y la función

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Right-Sided Cardiac Tumors Detected by Transesophageal Echocardiography and Its Usefulness in Differentiating the Benign From the Malignant Ones

Cited by 48 publications

References 3 publications

Primary cardiac sarcoma

Primary cardiac sarcoma

Condrossarcoma mixóide de átrio direito

Hepatocarcinoma con invasión cardiovascular: comunicación de 5 casos y revisión de la literatura

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