Right hemispatial ipsilesional neglect with chronic right hemisphere strokes

Lamb, Damon G.; Burtis, D. Brandon; Haque, Salsabil; Zilli, Eduardo M.; Kesayan, Tigran; Harciarek, Michał; Heilman, Kenneth M.

doi:10.1080/13803395.2017.1347606

“…However, in the focal condition of the present study, healthy controls deviated their bisection significantly more rightwards than did the patients when the shorter segment was on the right. Thus, this result suggests that the mechanism of the visuospatial attentional changes seen in patients undergoing hemodialysis seems similar to that of the ipsilesional neglect observed in patients with right frontal-subcortical lesions (Bonato et al, 2019;Harciarek et al, 2012;Kim et al, 1999;Sacchetti et al, 2015;Williamson et al, 2018). Specifically, this result from the focal condition of this study is consistent with the right hemisphere approach-avoidance theory proposed by Denny-Brown and Chambers (1958) that posits that, within the right hemisphere, the injury to the frontal lobe releases the approach-related behaviors that increase the allocation of attention to the contralateral portion of the line.…”

Section: Discussionsupporting

confidence: 66%

“…There may be several phenomena contributing to these results. For example, in healthy older people, pseudoneglect diminishes and further, healthy older people are more accurate in both tasks that elicit leftward biases and tasks that elicit rightward biases (Williamson et al, 2018). Thus, it may be that patients with ESRD are more similar to older adults, potentially due to the disease/treatment-related accelerated brain aging.…”

Section: Discussionmentioning

confidence: 99%

Leftward Spatial Bias in Dialyzed Patients With End-Stage Renal Disease: A Sign of Right Hemispheric Attentional Activation or Impaired Left-Sided Disengagement?

Mańkowska

¹

,

Heilman

²

,

Biedunkiewicz

³

et al. 2022

RPsych

Self Cite

0

View full text Add to dashboard Cite

In the horizontal line bisection task, patients with end-stage renal disease (ESRD) treated with dialysis typically have an increase in the normal leftward attentional bias. It is not clear, however, whether this increased bias is related to an increase of attention toward left hemispace or impaired disengagement from left-sided stimuli. Non-demented patients with ESRD who were being treated with dialysis and demographically matched healthy controls attempted to bisect series of horizontal lines composed of two segments of unequal length and width, with the longer segment placed to the right or left. To test for the presence of a global spatial attentional bias, participants attempted to find the middle of the whole line. To test for focal attentional engagement and attentional disengagement, participants were asked to bisect only the longer segment of these compound lines. For the global condition, both patients and healthy controls were biased toward the longer segment and more so to the left. In the focal condition, when the longer segment was on the right side, both groups deviated their bisections toward the shorter segment. However, when in the focal condition the longer segment was on the left healthy controls deviated their bisection significantly more rightwards than did the patients, whereas with the longer segment on the right, the patients and healthy controls did not differ in their bias. These results suggest that the previously recognized dysfunction of the right fronto-subcortical attentional network in dialyzed patients might account for the results of the current study.

show abstract

“…Since the majority of studies did not report spatial biases separately for male and female participants, we also calculated the percentage of male participants in each study where this data was available. Nineteen studies did not report the sex of their participants and the data from the following studies were therefore not included in this analysis: (Andrews et al 2017;Barton et al 1998;Binetti et al 2011;Corazzini et al 2005;Daini et al 2008;Doricchi et al 2002;Gassama et al 2011;Grossi et al 1999;Hatin et al 2012;Luauté et al 2012;Mennemeier et al 1997Mennemeier et al , 2001Plummer et al 2006;Richard et al 2004;Striemer and Danckert 2010;Vallar et al 2000;Veronelli et al 2014b;Williamson et al 2018;Zeller and Hullin 2018).…”

Section: Moderatorsmentioning

confidence: 99%

“…In other cases, the standard deviation was calculated first from reported confidence intervals (Andrews et al 2017) or standard errors (Plummer et al 2006;Striemer and Danckert 2010;Williamson et al 2018) before proceeding to the effect size calculation. The rationale for the decisions taken in each study are reported in Table 1.…”

Section: Effect Size Estimatesmentioning

confidence: 99%

See 1 more Smart Citation

A meta-analysis of line bisection and landmark task performance in older adults

Learmonth¹,

Παπαδάτου-Παστού²

2021

Preprint

3

0

View full text Add to dashboard Cite

Young adults exhibit a small asymmetry of visuospatial attention that favours the left side of space relative to the right (pseudoneglect). However, it remains unclear whether this leftward bias is maintained, eliminated or shifted rightward in older age. Here we present two meta-analyses that aimed to identify whether adults aged ≥50 years old display a group-level spatial attention bias, as indexed by the line bisection and the landmark tasks. A total of 69 datasets from 65 studies, involving 1654 participants, were analysed. In the meta-analysis of the line bisection task (n = 63), no bias was identified for studies where the mean age was ≥50, but there was a clear leftward bias in a subset where all individual participants were aged ≥50. There was no moderating effect of the participant’s age or sex, line length, line position, nor the presence of left or right cues. There was a small publication bias in favour of reporting rightward biases. Of note, biases were slightly more leftward in studies where participants had been recruited as part of a stand-alone older group, compared to studies where participants were recruited as controls for a clinical study. Similarly, no spatial bias was observed in the meta-analysis of the landmark task, although the number of studies included was small (n = 6). Overall, these results indicate that over 50s maintain a group-level leftward bias on the line bisection task, but more studies are needed to determine whether this bias can be modulated by stimulus- and/or state-dependent factors.

show abstract

A Meta-Analysis of Line Bisection and Landmark Task Performance in Older Adults

Learmonth

¹

,

Παπαδάτου-Παστού

²

2021

View full text Add to dashboard Cite

Young adults exhibit a small asymmetry of visuospatial attention that favours the left side of space relative to the right (pseudoneglect). However, it remains unclear whether this leftward bias is maintained, eliminated or shifted rightward in older age. Here we present two meta-analyses that aimed to identify whether adults aged ≥50 years old display a group-level spatial attention bias, as indexed by the line bisection and the landmark tasks. A total of 69 datasets from 65 studies, involving 1654 participants, were analysed. In the meta-analysis of the line bisection task (n = 63), no bias was identified for studies where the mean age was ≥50, but there was a clear leftward bias in a subset where all individual participants were aged ≥50. There was no moderating effect of the participant’s age or sex, line length, line position, nor the presence of left or right cues. There was a small publication bias in favour of reporting rightward biases. Of note, biases were slightly more leftward in studies where participants had been recruited as part of a stand-alone older group, compared to studies where participants were recruited as controls for a clinical study. Similarly, no spatial bias was observed in the meta-analysis of the landmark task, although the number of studies included was small (n = 6). Overall, these results indicate that over 50s maintain a group-level leftward bias on the line bisection task, but more studies are needed to determine whether this bias can be modulated by stimulus- or state-dependent factors.

show abstract

Right hemispatial ipsilesional neglect with chronic right hemisphere strokes

Cited by 10 publications

References 46 publications

Leftward Spatial Bias in Dialyzed Patients With End-Stage Renal Disease: A Sign of Right Hemispheric Attentional Activation or Impaired Left-Sided Disengagement?

Leftward Spatial Bias in Dialyzed Patients With End-Stage Renal Disease: A Sign of Right Hemispheric Attentional Activation or Impaired Left-Sided Disengagement?

A meta-analysis of line bisection and landmark task performance in older adults

A Meta-Analysis of Line Bisection and Landmark Task Performance in Older Adults

Contact Info

Product

Resources

About