Rift Valley fever: a sero-epidemiological survey among pregnant women in Mozambique

Niklasson, B; Liljestrand, Jerker; Bergström, Staffan; Peters, C. J.

doi:10.1017/s0950268800068011

Cited by 27 publications

(21 citation statements)

References 9 publications

(5 reference statements)

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“…Surveillance of cattle in the same province in 1996 and 2001 revealed a seroprevalence of 37% and 53%, respectively [9]. A seroprevalence of 2% (28/1163) in humans was found in a study conducted from 1981 to 1983 in 8 of the 10 provinces of Mozambique [10].…”

Section: Introductionmentioning

confidence: 99%

Serological Evidence of Rift Valley Fever Virus Circulation in Sheep and Goats in Zambézia Province, Mozambique

et al. 2013

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Rift Valley fever (RVF) is endemic in most parts of Africa and has also been reported to occur in the Arabian Peninsula. It is responsible for significant morbidity and mortality, particularly in livestock, but also in humans. During the last two decades several outbreaks of RVF have been reported in countries in Southern Africa. In contrast to other countries, no clinical disease has been reported in Mozambique during this period. In a serological study conducted in 2007 in five districts of Zambézia Province, Mozambique, of a total of 654 small ruminants sampled (277 sheep and 377 goats), 35.8% of sheep sera and 21.2% of goat sera were positive for RVF virus (RVFV) antibodies in a virus neutralization test (VN) and in an IgG enzyme-linked immunosorbent assay (ELISA). In 2010, a cross-sectional survey was conducted in 313 sheep and 449 goats in two districts of the same province. This study revealed an overall seropositivity rate of 9.2% in sheep and 11.6% in goat and an increased likelihood of being seropositive in older animals (OR = 7.3; p<0.001) using an IgG ELISA. 29 out of 240 animals assessed for RVF specific IgM by ELISA were positive, suggesting recent exposure to RVFV. However, a longitudinal study carried out between September 2010 and April 2011 in a cohort of 125 of these animals (74 sheep and 51 goats) failed to demonstrate seroconversion. The results of the study indicate that RVFV circulates sub-clinically in domestic small ruminants in Zambézia Province.

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Section: Introductionmentioning

confidence: 99%

Serological Evidence of Rift Valley Fever Virus Circulation in Sheep and Goats in Zambézia Province, Mozambique

et al. 2013

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“…The first evidence of RVFV in Mozambique was documented as early as the 1960s ( 1 ). Endemicity was subsequently confirmed in the 1980s by a prevalence study that identified virus-specific antibodies in 2% of pregnant women ( 2 ) and in the 1990s by serosurveillance in Zambezia Province, which showed that cattle had been infected with RVFV ( 3 ). …”

mentioning

confidence: 99%

Antibodies against Rift Valley Fever Virus in Cattle, Mozambique

Lagerqvist¹,

Moiane²,

Mapaco³

et al. 2013

Emerg. Infect. Dis.

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“…35 The virus has not shown direct human-to-human transmission, and there have been only a few documented cases of vertical transmission. 36–38 …”

Section: Epidemiologymentioning

confidence: 99%

“…28,66,67 Even though isolated cases of vertical transmission have been documented, 36–38 there appears to be no increase in apparent miscarriage in pregnant women. There is also no documented human-to-human transmission; infection of people appears to be limited to either mosquito bites or exposure to high titer animal tissues.…”

Section: Clinical Presentationmentioning

confidence: 99%