Ridge alterations after implant placement in fresh extraction sockets or in healed crests: An experimental in vivo investigation

Vignoletti, Fabio; Sanz‐Esporrín, Javier; Sanz‐Martín, Ignacio; Núñez, Lucía González; Luengo, Fernando; Sanz, Mariano

doi:10.1111/clr.13421

Cited by 8 publications

(23 citation statements)

References 30 publications

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“…The gradual peri-implant crestal bone remodeling will occur once implants have been placed [ 1 ]. It is a complex multi-factorial phenomenon and is influenced by several clinician-, patient-, and implant-related factors [ 2 , 3 ].…”

Section: Introductionmentioning

confidence: 99%

Effect of microthread design on the preservation of marginal bone around immediately placed implants: a 5-years prospective cohort study

et al. 2021

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Background This study aimed to evaluate the effect of the microthread design at the implant neck on the preservation of marginal bone around immediately-placed implants in a 5-year follow up. Methods Thirty patients received 41 immediately placed implants which were randomly assigned to treatment groups with microthreaded implants (test group, n = 22) or threaded implants (control group, n = 19). Clinical and radiographic analyses were carried out after 1 and5 years. Plaque index, bleeding on probing, suppuration, probing depth and marginal bone loss were subject to evaluations. The results were analyzed with the T-test, Fisher’s exact test and Mann–Whitney U test. Results No implants failed; thirty-five implants (in 27 patients); 21 microthreaded and 14 threaded implants; completed the 5 year follow up. The mean values of the marginal bone loss in microthreaded and threaded groups were 1.12 ± 0.95 mm and 0.87 ± 0.78 mm, respectively during an observation period of 70.9 ± 10.4 months; the differences in marginal bone loss and other pre-implant parameters were not significant between groups (P > 0.05). Conclusion Both implant designs showed acceptable results in terms of the clinical parameters and marginal bone level. Within the limitation of this study, the results did not demonstrate any superiority of the microthread design compared to threaded one in marginal bone preservation around immediately placed implants over 5 years of loading.

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Section: Introductionmentioning

confidence: 99%

Effect of microthread design on the preservation of marginal bone around immediately placed implants: a 5-years prospective cohort study

et al. 2021

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“…New surgical methods, like the socket-shield technique [ 169 , 170 ], bone-ring technique [ 171 , 172 ], flapless protocols, and ridge augmentation have improved our understanding of peri-implant tissue healing. The influence of immediate/delayed implant placement on the peri-implant bone [ 173 ] and soft-tissue [ 174 ] formation has been well documented [ 175 , 176 ]. Post-extraction socket healing, with or without implants [ 177 ], has been tested, allowing the basic protocol to be modified to prevent dehiscence [ 178 ] or manage the jumping distance between implant and vestibular bone [ 179 ].…”

Section: Appendix A1 Research In Non-human Primatesmentioning

confidence: 99%

Pre-Clinical Models in Implant Dentistry: Past, Present, Future

et al. 2021

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Biomedical research seeks to generate experimental results for translation to clinical settings. In order to improve the transition from bench to bedside, researchers must draw justifiable conclusions based on data from an appropriate model. Animal testing, as a prerequisite to human clinical exposure, is performed in a range of species, from laboratory mice to larger animals (such as dogs or non-human primates). Minipigs appear to be the animal of choice for studying bone surgery around intraoral dental implants. Dog models, well-known in the field of dental implant research, tend now to be used for studies conducted under compromised oral conditions (biofilm). Regarding small animal models, research studies mostly use rodents, with interest in rabbit models declining. Mouse models remain a reference for genetic studies. On the other hand, over the last decade, scientific advances and government guidelines have led to the replacement, reduction, and refinement of the use of all animal models in dental implant research. In new development strategies, some in vivo experiments are being progressively replaced by in vitro or biomaterial approaches. In this review, we summarize the key information on the animal models currently available for dental implant research and highlight (i) the pros and cons of each type, (ii) new levels of decisional procedures regarding study objectives, and (iii) the outlook for animal research, discussing possible non-animal options.

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“…Although immediate implant placement is effective in preservation of the alveolar bone dimensions but it fails to completely prevent the postextraction dimensional changes (Moy et al, 2016 ;Vignoletti et al, 2019). Therefore, attempts were done regarding placement of various biomaterials in the peri-implant gap to increase the immediate implant stability and to minimize or even prevent the post-extraction bone dimensional changes if possible.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Melatonin and Hyaluronic Acid Mixture on Hard Tissue Dimensional Changes Around Immediate Post-Extraction Implants.

Nasr

Shoeib

Darhous

et al. 2022

Egyptian Dental Journal

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Background: Both melatonin (MLT) and Hyaluronic acid (HA) are widely used in the dental field especially in implant therapy due to their well known physiochemical properties and biologic effects that boost hard and soft tissues healing.Aim: Assessing the effect of local application of a mixture of HA and MLT to the implant surface and peri-implant gap in immediate implants.Subjects and Methods: Twenty-four subjects with teeth scheduled for extraction of hopeless teeth in the inter-bicuspid region were equally divided between test group (immediate implant with HA and MLT mixture) and a control group (immediate implant alone). CBCT scans were done immediately after implant placement and 6 months postoperatively to evaluate the bone changes in terms of vertical, horizontal bone dimensional and density changes. Results:At the end of the study, the peri-implant vertical and horizontal buccal bone changes in test group recorded lower mean value compared to control group with no statistical significant difference between both groups with mean for test group (-0.97±0.265 ; -0.33±0.222) and control group (-1.08±0.275 ; -0.41±0.371) (p=0.329 ; p=0.543) respectively. As for the increase in bone density, there was a statistical difference between both groups in favor of the test group, with median and range [58.45 (8 -110), 18.1 (0 -70)] for test and control groups respectively. Conclusions:Within the limitations of this study, topical application of MLT and HA mixture might have a beneficial impact on immediate implant placement specifically in reduction of buccolingual dimensional changes and increasing bone density.

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Ridge alterations after implant placement in fresh extraction sockets or in healed crests: An experimental in vivo investigation

Cited by 8 publications

References 30 publications

Effect of microthread design on the preservation of marginal bone around immediately placed implants: a 5-years prospective cohort study

Effect of microthread design on the preservation of marginal bone around immediately placed implants: a 5-years prospective cohort study

Pre-Clinical Models in Implant Dentistry: Past, Present, Future

The Effect of Melatonin and Hyaluronic Acid Mixture on Hard Tissue Dimensional Changes Around Immediate Post-Extraction Implants.

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