Riboflavin as a dentin crosslinking agent: Ultraviolet A versus blue light

Fawzy, A.; Nitisusanta, Lorraine I.; Iqbal, Kulsum; Daood, Umer; Neo, Jaclyn L.

doi:10.1016/j.dental.2012.09.009

Cited by 59 publications

(65 citation statements)

References 28 publications

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“…Low-dose riboflavin has also been tested as dentin crosslinking agent in conjunction with UVA or dental blue light with good success [124,134]. These studies have shown effective MMP inhibition and stabilization of the adhesive interfaces [124], as well as increased mechanical properties, stability, and resistance to dentin collagen degradation [135].…”

Section: Collagen Cross-linking Agentsmentioning

confidence: 97%

Mechanisms of degradation of the hybrid layer in adhesive dentistry and therapeutic agents to improve bond durability—A literature review

et al. 2016

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Section: Collagen Cross-linking Agentsmentioning

confidence: 97%

Mechanisms of degradation of the hybrid layer in adhesive dentistry and therapeutic agents to improve bond durability—A literature review

et al. 2016

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“…126,127 An increase in immediate dentin bond strength may be achievable even with shorter treatment times, 128,129 and improved durability of long-term bond strength has also been indicated. 81,130 Riboflavin has also been successfully tested, but the need for ultraviolet light or separate cross-linker light curing 131,132 reduces its clinical acceptability.…”

Section: Use Of Cross-linkersmentioning

confidence: 99%

Dentin Bonding: Can We Make it Last?

Tjäderhane

2015

Operative Dentistry

164

144

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Bond strength to dentin decreases with time because of the hydrolytic degradation of the hybrid layer components dentin collagen and adhesive resin. Inhibition of enzymes responsible for the collagen degradation may improve the bond strength durability. SUMMARYIn dentin bonding, contemporary dental adhesive systems rely on formation of the hybrid layer, a biocomposite containing dentin collagen and polymerized resin adhesive. They are usually able to create at least reasonable integrity of the hybrid layer with high immediate bond strength. However, loss of dentinbonded interface integrity and bond strength is commonly seen after aging both in vitro and in vivo. This is due to endogenous collagenolytic enzymes, matrix metalloproteinases, and cysteine cathepsins, responsible for the timedependent loss of hybrid layer collagen. In addition, the hydrophilic nature of adhesive systems creates problems that lead to suboptimal hybrid layers. These problems include, for example, insufficient resin impregnation of dentin, phase separation, and a low rate of polymerization, all of which may reduce the longevity of the bonded interface.Preservation of the collagen matrix integrity by inhibition of endogenous dentin proteases is key to improving dentin bonding durability. Several approaches to retain the integrity of the hybrid layer and to improve the long-term dentin bond strength have been tested. These include the use of enzyme inhibitors, either separately or as incorporated into the adhesive resins; increase of collagen resistance to enzymatic degradation; and elimination of water from the interface to slow down or eliminate hydrolytic loss of the hybrid layer components. This review looks at the principles, current status, and future of the different techniques designed to prevent the loss of hybrid layer and bond strength.

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“…The procedure followed for SEM evaluation is based on established protocols carried out in previous studies [30]. The restored teeth (n = 4 /group) were sectioned perpendicularly to the resin-dentin interface to obtain 1 mm thick resin-dentin slabs (n = 12/group) were prepared for SEM examination of the resin-dentin interface morphology.…”

Section: Sem Evaluationmentioning

confidence: 99%

Effect of grape seed extract on the bond strength and durability of resin-dentin interface

Paulose

Fawzy

2017

Journal of Adhesion Science and Technology

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To investigate the effect of grape seed extract (GSE) on the bond strength and durability of the resin-dentin interface using a twostep etch-and-rinse (E&R) and a universal adhesive (UA) system. Additionally the effect of dry and wet bonding on the interface created by UA was evaluated. The effect of GSE on the morphology, nanoleakage expression (NE) and bond strength of the resin-dentin interface was evaluated by scanning electron microscopy (SEM) evaluation, interfacial NE and micro-tensile bond strength (μ-TBS) testing respectively. Dentin surfaces of sound molars were exposed, acid-etched, and treated with cross-linking pre-conditioners followed by application of adhesive, light-cured, and built up with restorative composite in an incremental manner. After the restored teeth were left for 24 h in distilled water for polymerisation, dentin beams were sectioned for μ-TBS testing and dentin slabs for SEM and NE. Pretreatment with GSE did not significantly alter the μ-TBS and NE of any adhesives compared to their respective controls at 24 h and 1 year. Significant decrease in μ-TBS and significant increase in NE after 1 year of storage compared to 24 h results is observed. SEM evaluation showed good hybrid layer formation at 24 h but shows a degraded appearance after 1 year especially with wet bonding technique. Pretreatment of acid-etched dentin with 6.5% GSE w/v for 1 min, before the application of the adhesive did not significantly improve the bond strength and durability of the resin-dentin interface created by the two-step E&R adhesive and UA. Dry bonding technique for UA seemed more effective.

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Riboflavin as a dentin crosslinking agent: Ultraviolet A versus blue light

Cited by 59 publications

References 28 publications

Mechanisms of degradation of the hybrid layer in adhesive dentistry and therapeutic agents to improve bond durability—A literature review

Mechanisms of degradation of the hybrid layer in adhesive dentistry and therapeutic agents to improve bond durability—A literature review

Dentin Bonding: Can We Make it Last?

Effect of grape seed extract on the bond strength and durability of resin-dentin interface

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