Rhabdomyosarcome pléomorphe paratesticulaire de l'adulte: diagnostic et prise en charge

Kourda, Nadia; Atat, Rabii El; Derouiche, A.; Bettaib, I.; Baltagi, S Ben Jilani; Zermani, R

doi:10.1016/j.canrad.2007.05.005

Cited by 14 publications

(5 citation statements)

References 8 publications

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“…Initial radical surgery including high ligation of the spermatic cord followed by adjuvant therapy is the current treatment of choice; high-dose radiotherapy is thought to be an alternative treatment could improve the therapeutical outcome [ 8 ]. Local recurrence should be treated by radiotherapy and metastases should be treated by chemotherapy [ 9 ]. Chemotherapy was reserved for palliation in the presence of advanced or metastatic disease.…”

Section: Discussionmentioning

confidence: 99%

Primary epididymis malignant triton tumor: case report and review of the literature

Gao

Song

et al. 2015

Eur J Med Res

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Background Malignant triton tumor (MTT) is a rare and histological complexity characterized by a mixture of peripheral nerve sheath tumors and with rhabdomyoblastic differentiation. It follows a particularly malignant course. Case presentationIn the present study, we report the first MTT of epididymis. The patient is a 22-year-old male presented with swelling in the left scrotum over a 2-month period. He did not have the history or symptoms of neurofibromatosis type 1. A mass measured about 3 cm × 4 cm was found in the left epididymis by ultrasound and CT scan. It was diagnosed as epididymis tumor and underwent exploration; intraoperative frozen section was diagnosed malignant tumor and treated with radical orchidoepididymectomy. The pathological report was malignant triton tumor. Despite taken high-dose radiation therapy and followed by chemotherapy for four cycles, he was died of progressive disease with multiple metastases 26 months after surgery. The clinic pathologic characteristics and optimal treatment strategy are reviewed.

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Section: Discussionmentioning

confidence: 99%

Primary epididymis malignant triton tumor: case report and review of the literature

Gao

Song

et al. 2015

Eur J Med Res

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“…When the tumor invades the scrotum, unilateral scrotal resection is needed. If lymph node metastasis in the spermatic cord, pelvic cavity, or retroperitoneal area is considered before surgery, active regional lymph node dissection is recommended [ 6 , 29 , 30 ]. Further comprehensive treatment measures will be determined on the basis of pathological results after surgery.…”

Section: Discussionmentioning

confidence: 99%

Treatment of primary epididymal adenocarcinoma: a case report and review of the literature

Xiao,

You,

Dong

et al. 2024

J Med Case Reports

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Background Epididymal tumors, especially malignant tumors, have low incidence and are rare in our clinical work. However, they may progress quickly and have poor prognosis. For such rare clinical cases with extremely low incidence rates, and as they are prone to misdiagnosis and missed diagnosis and have a very poor prognosis, clinical workers need to pay special attention and consider the possibility of primary epididymal malignant tumors. Case report A 63-year-old Chinese male patient from Asia was admitted due to scrotal pain. Upon examination, an abnormal lesion was found in the right epididymal region. After thorough evaluation, surgical resection was performed, and the postoperative pathological result confirmed the presence of epididymal adenocarcinoma. After further ruling out secondary lesions, primary epididymal adenocarcinoma was considered. Right retroperitoneal lymph node dissection was performed under laparoscopic for treatment, and 1/11 lymph node metastasis was detected after surgery. The patient is currently under close follow-up. Conclusions The number of clinical cases of primary epididymal malignant tumors is very limited, there is currently no standardized diagnosis and treatment process, and there is a lack of systematic evaluation methods regarding the effectiveness of different treatment options such as chemotherapy, radiotherapy, immunotherapy, and targeted therapy. In addition, the outcome is difficult to predict. In this article, we reviewed relevant literature and systematically elaborated on the diagnosis and treatment of epididymal malignant tumors, hoping to provide useful information for relevant experts.

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“…In the metastatic setting, many protocols of chemotherapy have been tried. VAC, IVA, and VIE protocols (V: vincristine, A: actinomycin, I: ifosfamide, E: etoposide, and C: cyclophosphamide) and better results were observed with VAC protocol [ 11 – 13 ]. In our serie two cases received chemotherapy by MAI, and one patient was treated by VAC.…”

Section: Discussionmentioning

confidence: 99%

Para testicular rhabdomyosarcoma in adults: three case reports and review of literature

Boudahna¹,

Benbrahim²,

Amaadour³

et al. 2014

Pan Afr Med J

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Paratesticular embryonal rhabdomyosarcoma (RMS) is a rare tumor arising from the mesenchymal tissues of the spermatic cord, epididymis, testis and testicular tunics. We report three cases of adult paratesticular RMS, two embryonic and one pleomorphic rhabdomyosarcoma. All the patients underwent diagnostic orchidectomy. The work up investigations revealed lung metastases. Chemotherapy with Ifosfamide and Doxorubicin was used in two cases, whereas Vincristin- Actinomycin D and Cyclophosphamide was received in one case. An objective partial response was reported in 2 cases, with complete response in one case. Paratesticular RMS is a rare and aggressive tumor. Because of the absence of protocols designed specifically for adult patients, it is necessary to follow therapeutic guidelines in pediatric protocols.

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Rhabdomyosarcome pléomorphe paratesticulaire de l'adulte: diagnostic et prise en charge

Cited by 14 publications

References 8 publications

Primary epididymis malignant triton tumor: case report and review of the literature

Primary epididymis malignant triton tumor: case report and review of the literature

Treatment of primary epididymal adenocarcinoma: a case report and review of the literature

Para testicular rhabdomyosarcoma in adults: three case reports and review of literature

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