Thermoresponsive liquid marbles were prepared from water and 1-bromo-3-fluoro-4-iodobenzene (BFI) powder with a melting point of 46.5°C. The liquid marble can be floated on the surface of bulk water at room temperature, which is lower than the melting point of BFI. When the temperature of bulk water was increased above the melting point, the liquid marble disintegrated to leak the interior water to bulk water. Heating can be applied as a trigger of a chemical reaction between the interior reactant and another reactant in bulk water.Recently, liquid marbles that stabilize a water droplet using a hydrophobic powder at the gasliquid interface have been garnering increased attention as a new technique for handling, hauling, and preservation of liquids.1 For example, the stability of stimuli-responsive liquid marbles can be controlled by changing the powder wettability adsorbed to a water droplet. Fujii et al. 3 have reported the preparation of pH-responsive liquid marbles using polystyrene latex particles functionalized with the tertiary amino group-containing poly [2-(N,N-diethylamino)ethyl methacrylate] (pDEA, pK a = ca. 7.0) hair prepared by dispersion polymerization. The liquid marble can be floated on the surface of basic water owing to the hydrophobic deprotonated pDEA hair. Conversely, the liquid marble immediately disintegrates on exposure to acidic vapor due to protonation of the pDEA hair.We previously reported the preparation of thermoresponsive liquid marbles using poly(N-isopropylacrylamide) (pNIPAM) powder possessing a lower critical solution temperature (LCST). 4 Although pNIPAM is hydrated to dissolve molecularly in water below the LCST due to hydrogen-bonding interactions between the pendant amide groups and water molecules, it becomes hydrophobic above the LCST due to breaking of the hydrogen-bonding interactions.5 The liquid marble covered with pNIPAM powder containing a water droplet can be floated on the surface of bulk water above the LCST for more than one day. Upon cooling the bulk water below the LCST, the liquid marble disintegrated due to hydration of the pNIPAM powder. The thermoresponsive liquid marble formed from pNIPAM can be destabilized by cooling. Xu et al. 6 have reported infrared radiation (i.e. heating) responsive liquid marbles. To the best of our knowledge, thermoresponsive liquid marbles destabilized by heating above melting point have not been reported. Therefore, we have focused our attention on hydrophobic compounds with low melting points as hydrophobic powders to prepare thermoresponsive liquid marbles. If a hydrophobic powder with a low melting point is used to prepare a liquid marble, the liquid marble should be destabilized by heating above the melting point. The advantage of such thermoresponsive liquid marbles can be the control of the disintegration temperature by the melting point of the hydrophobic powder.In this report, we studied thermoresponsive liquid marbles prepared from water and hydrophobic 1-bromo-3-fluoro-4-iodobenzene (BFI, 97+%, Wako Pure Chemical) pow...