Revisiting the Role of Biologically Active Natural and Synthetic Compounds as an Intervention to Treat Injured Nerves

Souza, Natália Melo; Gonçalves, Mateus Figueiredo; Ferreira, Luiz Fernando Romanholo; Bilal, Muhammad; Iqbal, Hafiz M.N.; Soriano, Renato Nery

doi:10.1007/s12035-021-02473-z

Cited by 2 publications

(2 citation statements)

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“…In a recent publication by Souza et al [63], a comprehensive and meticulous review was conducted to investigate the efficacy and potential applications of a wide range of pharmacotherapeutic agents in various therapeutic contexts. The study delved into both herbal medicines, such as gingko biloba and curcumin, and conventional medicine like dexamethasone.…”

Section: Pharmacotherapymentioning

confidence: 99%

“…Gingko biloba, known for its antioxidant and anti-inflammatory properties, has shown promise in improving cognitive function and reducing neuronal damage in neurodegenerative disorders [61]. Curcumin, a compound found in turmeric, has also exhibited neuroprotective effects and anti-inflammatory properties, showing potential in mitigating neurodegenerative processes [63]. The inclusion of these herbal medicines in the review broadens the scope of potential therapeutic interventions and emphasizes the importance of considering alternative approaches to conventional medicine.…”

Section: Pharmacotherapymentioning

confidence: 99%

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Innovations in Peripheral Nerve Regeneration

Lam,

Leung

2024

Bioengineering

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The field of peripheral nerve regeneration is a dynamic and rapidly evolving area of research that continues to captivate the attention of neuroscientists worldwide. The quest for effective treatments and therapies to enhance the healing of peripheral nerves has gained significant momentum in recent years, as evidenced by the substantial increase in publications dedicated to this field. This surge in interest reflects the growing recognition of the importance of peripheral nerve recovery and the urgent need to develop innovative strategies to address nerve injuries. In this context, this article aims to contribute to the existing knowledge by providing a comprehensive review that encompasses both biomaterial and clinical perspectives. By exploring the utilization of nerve guidance conduits and pharmacotherapy, this article seeks to shed light on the remarkable advancements made in the field of peripheral nerve regeneration. Nerve guidance conduits, which act as artificial channels to guide regenerating nerves, have shown promising results in facilitating nerve regrowth and functional recovery. Additionally, pharmacotherapy approaches have emerged as potential avenues for promoting nerve regeneration, with various therapeutic agents being investigated for their neuroprotective and regenerative properties. The pursuit of advancing the field of peripheral nerve regeneration necessitates persistent investment in research and development. Continued exploration of innovative treatments, coupled with a deeper understanding of the intricate processes involved in nerve regeneration, holds the promise of unlocking the complete potential of these groundbreaking interventions. By fostering collaboration among scientists, clinicians, and industry partners, we can accelerate progress in this field, bringing us closer to the realization of transformative therapies that restore function and quality of life for individuals affected by peripheral nerve injuries.

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Section: Pharmacotherapymentioning

confidence: 99%

Section: Pharmacotherapymentioning

confidence: 99%