Revisiting cancer 15 years later: Exploring mortality among agricultural and non‐agricultural workers in the Serrana Region of Rio de Janeiro

Krawczyk, Noa; Santos, Aline Araújo dos; Lima, Jaime; Meyer, Armando

doi:10.1002/ajim.22660

Cited by 7 publications

(3 citation statements)

References 50 publications

(70 reference statements)

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“…Elevated stomach cancer risk in comparison to the general population has been reported in several studies of agricultural workers (Blair and Freeman 2009, Bucchi et al 2004, Krawczyk et al 2017.…”

Section: Discussionmentioning

confidence: 89%

“…Most studies of farmers showed a strong deficit of lung and laryngeal cancers (Blair and Freeman 2009, Waggoner et al 2011, Leveque-Morlais et al 2015, Kachuri et al 2017, Krawczyk et al 2017 attributed to a lower smoking prevalence in agricultural workers than in the general population. We did not observe such a deficit in the present study, with nonsignificant SMRs of 0.91 in men and 1.31 in women.…”

Section: Discussionmentioning

confidence: 99%

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A cohort study of banana plantation workers in the French West Indies: first mortality analysis (2000–2015)

Luce

Dugas

Vaidie

et al. 2019

Environ Sci Pollut Res

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Chloredecone, an organochlorine insecticide, was widely used in the French West Indies banana plantations. We set up a cohort of banana plantation workers who worked between 1973 and 1993, the period of authorized use of chlordecone. Vital status and causes of death were collected from French national registries. Workers were followed-up from 1 January 2000 to 31 December 2015. Cause-specific mortality in the cohort was compared to that of the general population of the French West Indies by computing standardized mortality ratios (SMRs). A total of 11112 workers (149526 person-years, 77% men) were included in the mortality analysis, and 3647 deaths occurred over the study period. There was a slight deficit in all-cause mortality, which was statistically significant in men (SMR=0.93, 95% CI 0.89-0.96), but not in women (SMR=0.96, 95% CI 0.89-1.04). All-cancer mortality did not differ significantly from that of the general population (men: SMR=0.96, 95% CI 0.90-1.03; women: SMR=1.04, 95%CI 0.89-1.21). Significant excesses of deaths were observed for stomach cancer in women (SMR=1.94, 95% CI 1.24-2.89) and pancreatic cancer in women farm owners (SMR=2.31, 95% CI 1.06-4.39). Mortality from prostate cancer was similar to that of the general population in the whole cohort (SMR=1.00; 95% CI 0.89-1.13), and nonsignificantly elevated among farm workers (SMR=1.10, 95%CI 0.87-1.36). Non-significant increases in mortality were also observed for lung cancer in women, leukemia in men and non-Hodgkin lymphoma in both genders.

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Section: Discussionmentioning

confidence: 89%

Section: Discussionmentioning

confidence: 99%

A cohort study of banana plantation workers in the French West Indies: first mortality analysis (2000–2015)

Luce

Dugas

Vaidie

et al. 2019

Environ Sci Pollut Res

View full text Add to dashboard Cite

show abstract

“…In contrast, the south region comprises small farms over the total agricultural area [ 27 ]. Although there is evidence of acute and chronic adverse health effects of pesticide exposure in Brazilian farmers [ 28 , 29 , 30 , 31 , 32 ], to our knowledge, no studies have examined the association between farming, pesticide exposure, and AKF in Brazil. Our study evaluated time trends in AKF mortality rates in Brazilian south and midwest regions, where most agricultural production is located, for the period 1980–2014.…”

Section: Introductionmentioning

confidence: 99%

Acute Kidney Failure among Brazilian Agricultural Workers: A Death-Certificate Case-Control Study

Meyer

Santos

Asmus

et al. 2022

IJERPH

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Recent evidence suggests that pesticides may play a role in chronic kidney disease. However, little is known about associations with acute kidney failure (AKF). We investigated trends in AKF and pesticide expenditures and associations with agricultural work in two Brazilian regions with intense use of pesticides, in the south and midwest. Using death certificate data, we investigated trends in AKF mortality (1980–2014). We used joinpoint regression to calculate annual percent changes in AKF mortality rates by urban/rural status and, in rural municipalities, by tertiles of per capita pesticide expenditures. We then compared AKF mortality in farmers and population controls from 2006 to 2014 using logistic regression to estimate odds ratios and 95% confidence intervals adjusted by age, sex, region, education, and race. AKF mortality increased in both regions regardless of urban/rural status; trends were steeper from the mid-1990s to 2000s, and in rural municipalities, they were higher by tertiles of pesticide expenditures. Agricultural workers were more likely to die from AKF than from other causes, especially at younger ages, among females, and in the southern municipalities. We observed increasing AKF mortality in rural areas with greater pesticide expenditures and an association of AKF mortality with agricultural work, especially among younger workers.

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Pollution of Water and Food by Hormonally Active Pesticides and Drugs (Human and Veterinary): Focus on Emerging Countries: Emerging Contaminants with Endocrine Disruption Potential in Brazil

Solano

2020

Challenges in Endocrine Disruptor Toxicology and Risk Assessment

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Significant increases in agricultural production and productivity have been achieved in the last decades and Brazil has become one of the main players in world agribusiness with the largest consumption in absolute values of pesticides in the world. However, the consequences of a predatory model of production and development can cause problems of environmental contamination and human health either via water and food or by direct exposure of workers to different chemicals. Contaminants in Brazil are found in the environment, in the water, in the fresh food, grains, breast and cow's milk, everywhere. Therefore, it is not only a question of exposure, but in fact a problem of imposition. Available data published by Brazilian researchers are showing contamination of aquatic ecosystems and human population groups by persistent chemicals, hormones and pesticides suspected to have endocrine-disrupting properties. The most recent investigations on endocrine-disrupting chemicals detected in environmental and human samples are reported here as well as the current activities by official regulatory bodies. The legislation from 1988 is protective from the point of establishing cutting off criteria and non-approval for pesticides, but there is a big gap between what is in the law and what happens in practice. In conclusion, there is no structure to monitor all chemicals and products consumed and released in the country, which results in recurrent human and environmental contamination. Overall, the massive role of Brazil within the international food and agro-energy supply makes the effects of pollution not only a local problem but also a global concern.

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Revisiting cancer 15 years later: Exploring mortality among agricultural and non‐agricultural workers in the Serrana Region of Rio de Janeiro

Abstract: Agricultural workers may be at increasing risk for cancer and other mortality. Efforts are needed to investigate distinct risk-factors among this group. Am. J. Ind. Med. 60:77-86, 2017. © 2016 Wiley Periodicals, Inc.

Cited by 7 publications

References 50 publications

A cohort study of banana plantation workers in the French West Indies: first mortality analysis (2000–2015)

A cohort study of banana plantation workers in the French West Indies: first mortality analysis (2000–2015)

Acute Kidney Failure among Brazilian Agricultural Workers: A Death-Certificate Case-Control Study

Pollution of Water and Food by Hormonally Active Pesticides and Drugs (Human and Veterinary): Focus on Emerging Countries: Emerging Contaminants with Endocrine Disruption Potential in Brazil

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