Revised World Health Organization Criteria-Defined Acute Myeloid Leukemia in a Large Cohort: Highlighting the Frequency and Characterization of Recategorized Cases
Abstract:Background: Application of the 2016 revised WHO criteria for categorization of acute myeloid leukemia (AML) highlights certain discrepancies from that of the 2008 WHO criteria. We thus analyzed the frequency, categorization patterns, and features of discrepant cases, and characterized the AML subtypes that had undergone major changes under the revised criteria. Methods: We divided the patients into the following seven categories based on the previous and the revised WHO criteria: AML with recurrent genetic abn… Show more
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