Revisão sistemática dos fatores associados à leptospirose no Brasil, 2000-2009

Human leptospirosis in the Federal District, Brazil, 2011-2015: eco-epidemiological characterization

“…The profi le of human leptospirosis in the FD was predominantly urban, which matches the eco-epidemiological profi le of the disease in other federal units of Brazil, where most of the population lives in large urban centers [5][6][7][8]18 . However, it should be considered that the regional distribution of these populations are predominantly urban and that the limits of separation associated with rural areas are often indistinct within a given region 13 .…”

“…Despite leptospirosis having less morbidity than dengue fever in the FD, the lethality of the disease is higher than infections caused by the dengue virus 11 . Another point to consider is that human leptospirosis in the FD may not have all cases reported due to the failure to recognize and diagnose the disease by the public health network 4,5 .…”

“…Moreover, bacterium is present in the urine of infected animals and under favorable conditions can remain viable in the environment for months 1,[4][5][6] .…”

“…The establishment of information and regional factors involved in human leptospirosis could guide the planning of public actions and policies for the prevention, control, and surveillance of this disease. The temporal cut-off for inclusion of the cases was determined from the day of the fi rst symptoms presented by the patients, considering the incubation period of the disease from 0-30 days 5 . The location of the residence and probable infection place (PIP) of each patient was determined through the Global Geographic Location System [Global Positioning System (GPS)].…”

“…The vulnerable population lives and works in these areas with scarce resources, low levels of social and health care, lack of basic sanitation, and environmental factors, such as high rainfall and recurrent fl oods during the rainy season 5,[7][8][9][10] .…”