Review on the Biocompatibility and Bioactivity of Forsterite: In Vitro and in Vivo studies

Avram, Alexandra; Mocanu, Aurora; Tomoaia, Gheorghe; Tomoaia-Cotişel, Maria

doi:10.56082/annalsarscibio.2022.1.167

Cited by 3 publications

(2 citation statements)

References 139 publications

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“…The bioactivity of hydroxyapatite can be improved by incorporating elements necessary for the human body into its structure. These elements can be: Mg, Si, Zn, Sr, Na, Cu, Ag, Se and constituents such as (SiO4) and (CO3) 2being proven by specialized literature that hydroxyapatite has the ability to very easily accept ions in the network to crystallize [43][44][45][46][47][48][49][50][51][52][53][54][55].…”

Section: Remineralization Of Dental Enamelmentioning

confidence: 99%

Perspectives of Oral Dental Care

PALTINEAN¹,

FLOREA²,

Tomoaia³

et al. 2022

AnnalsARSciBio

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This research focuses on debating the negative impact on dental enamel produced by unhealthy diet, some alcoholic and non-alcoholic drinks, smoking, drug use, inadequate hygiene conditions due to poor lifestyle and physical-chemical activities. These factors denature the quality of dental enamel, and the demineralization process begins resulting in caries and periodontal diseases. Caries are the most common diseases of the oral cavity that, if not treated in time, lead to dysfunctional mastication, impaired smile, gingival inflammation, abscess, and unbearable pain. The research also addresses the remineralization of dental enamel using materials and composites based on hydroxyapatite that are capable of producing beneficial effects for strong and healthy teeth. Evaluating caries prevention methods is absolutely essential, but the most important of all is educating children from an early age that healthy teeth require proper personal hygiene.

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Section: Remineralization Of Dental Enamelmentioning

confidence: 99%

Perspectives of Oral Dental Care

PALTINEAN¹,

FLOREA²,

Tomoaia³

et al. 2022

AnnalsARSciBio

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“…This review provides useful information on the development of innovative nanomaterials, made of nanoparticles, capable of interacting with the living system and producing positive responses in terms of integration. The importance of the use of nanostructured biomaterials in biomedical and pharmaceutical applications is of increasing interest in terms of their safety, biocompatibility and toxicity [335]. A part of the nanoscience of materials that is less known but that is gaining ground in the safe and efficient design of medicine is the interaction with the biological environment [336,337] to support and enhance a biological function.…”

Section: Nanoparticles Interaction With Biological Membranes and Livi...mentioning

confidence: 99%

Biomaterials With Enhanced Biological Functions for Medical Applications

Balint¹,

Paltinean²,

Tomoaia³

et al. 2021

AnnalsARSciBio

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Biomaterials and their use as implant coatings have been evaluated focusing on biocompatibility, biodegradability and constructive responses in terms of osseointegration, cell proliferation and cell adhesion. Biomaterials from natural (protein and polysaccharide) and synthetic (metallic, polymeric, ceramic and composite) sources have been identified. The role of biomaterials and implant coatings in the body through in vivo and in vitro experiments has been highlighted. In addition, methods for activating the surface of implants such as mechanical, chemical and physical ones are presented, as well as the classification of the deposition procedures but also of the interactions with the living system. This review addresses a topic with future challenges and perspectives in the biomedical field with the well-defined goal of maintaining and enhancing tissue elasticity, facilitating the healing of diseases suffered by patients and developing innovative materials capable of replacing or regenerating affected tissues.

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Antibacterial Effect of Hydroxyapatite and Silver

Avram¹,

Mocanu²,

Horovitz³

et al. 2022

AnnalsARSciPhysChem

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Synthetic hydroxyapatite (Ca10(PO4)6(OH)2, HAP) is widely used in regards to orthopedic applications due to its similarity to the mineral component in bone. However, while HAP aids with osseointegration it does nothing when it comes to orthopedic infections. Moreover, the prevalence of antibiotic resistance makes treatment even more difficult. In view of this, adding silver to hydroxyapatite has been a focus of many studies due to the combined bioactivity of HAP and excellent antibacterial properties of Ag. The present work brings a brief introduction to more recent studies regarding the HAP-silver combination and its effect on different pathogenic strains. The effect of silver on benign cells is also discussed based on in vitro cultures and in vivo studies.

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Review on the Biocompatibility and Bioactivity of Forsterite: In Vitro and in Vivo studies

Cited by 3 publications

References 139 publications

Perspectives of Oral Dental Care

Perspectives of Oral Dental Care

Biomaterials With Enhanced Biological Functions for Medical Applications

Antibacterial Effect of Hydroxyapatite and Silver

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