Review on Pharmacological Profile of Medicinal Vine: Tinospora cordifolia

Kumar, Antul; Paul, Amandeep; Singh, Gurwinder; Choudhary, Anuj

doi:10.9734/cjast/2019/v35i530196

Cited by 8 publications

(6 citation statements)

References 7 publications

(7 reference statements)

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“…Ethanolic extract of T. cordifolia fresh leaves (50 mg/kg) showed a significant decrease in the immobility period (force swim and tail immersion tests. In patients with chronic mental stress, serum glucose, triglyceride, cholesterol, anxiety, and depression were higher than in healthy men 31 . The patients were administered with T. cordifolia (3 g twice daily) powder and advised to do yoga daily.…”

Section: Antidiabetic Activitymentioning

confidence: 74%

Untitled

2022

IJPSR

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Natural products with medicinal value are becoming increasingly important in food preservation. Tinospora cordifolia, a plant commonly known as Guduchi, is highly beneficial in the medicinal field and has been used for centuries to treat various diseases. Due to the discovery of active components in Tinospora species and their potential for disease control, this plant has gained interest across the globe. Various pharmacological characteristics such as antioxidant, hepatoprotective, neuroprotective, antidiabetic and analgesic antitumor activities support its medicinal properties making it a promising herb with various health benefits. These biological activities of Tinospora species can be attributed due to the presence of a wide range of phytoconstituents, including alkaloids, flavonoids, lignans, Furano diterpene glucosides and sterols. The clinical importance of Tinospora cordifolia is included in this review to investigate its potential uses as an ingredient for the food industry. The future scope of the review remains in exploiting and isolating antimicrobial compounds to enable new and effective formulations in food preservation.

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Section: Antidiabetic Activitymentioning

confidence: 74%

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2022

IJPSR

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“…Tinocordiside is a glycoside well known for its traditional uses in treatment of neurological disorders such as ALS, Parkinson's disease, dementia, motor and cognitive deficits, and neuron loss in the spine and hypothalamus [23]. Immunomodulatory activity is also attributed to this compound [24] and for thrombolytic drugs [25].…”

Section: Resultsmentioning

confidence: 99%

Nonirritant and Cytocompatible Tinospora cordifolia Nanoparticles for Topical Antioxidant Treatments

González-Masís

Cubero-Sesín

Corrales-Ureña³

et al. 2020

International Journal of Biomaterials

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Tinospora cordifolia extract contains antioxidants such as polyphenols, and thus, it has been used as a natural phytochemical antioxidant therapeutic agent. Many of these compounds are insoluble or only partially soluble in water. In this study, we produced a novel aqueous nanoparticle formulation, with an average particle size of 182.9 ± 3.8 nm, to improve the dispersion of the bioactive compounds in water and to increment its bioavailability. The nanoparticles are composed of polyphenols, alkaloids, and glycosides. We studied the effect of this nanoparticle formulation on mouse 3T3 fibroblast cell viability and New Zealand rabbit dermal irritability tests. Concentrations of 2.5, 25, and 250 µg/mL resulted in similar cell viability to cells in culture media. An intermediate concentration of 12.45 mg/ml was used for the acute dermal irritability test. There were no severe alterations that compromised animal health. These results represent a precedent for application of such nanoparticles derived from plant stems, such as Tinospora cordifolia, in biomedicine and in antiaging cosmetic treatments.

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“…(37) The stem extract of T. cordifolia showed potent antiarrhythmic activity by normalization in PQRST waves as indicated by percentage of protection. (38)…”

Section: Antiarrhythmic Activitymentioning

confidence: 99%

Therapeutic Application, Phytoactives and Pharmacology of Tinospora cordifolia: An Evocative Review

Ahsan

Mishra

Badar

et al. 2023

Chin. J. Integr. Med.

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Tinospora cordifolia (Guduchi) is an important medicine in the Ayurvedic system of medication and is found in numerous classical texts for the treatment of various disorders such as jaundice, fever, skin diseases and diabetes. (1) T. cordifolia is a large, green glabrous, deciduous herbaceous plant. It belongs to the Menispermaceae family. (2) T. cordifolia is spread throughout India and China. Guduchi is the Hindi name of T. cordifolia, and it is a Hindu mythological term that refers to the heavenly elixir which is maintained the body in old age and helps to make it young. T. cordifolia is commonly known as Amrita, Guduchi Madhuparni,

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Review on Pharmacological Profile of Medicinal Vine: Tinospora cordifolia

Cited by 8 publications

References 7 publications

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Nonirritant and Cytocompatible Tinospora cordifolia Nanoparticles for Topical Antioxidant Treatments

Therapeutic Application, Phytoactives and Pharmacology of Tinospora cordifolia: An Evocative Review

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