Review on Greener and Safer Synthesis of Nitro Compounds

Badgujar, Dilip M.; Talawar, M. B.; Mahulikar, Pramod P.

doi:10.1002/prep.201500090

Cited by 36 publications

(29 citation statements)

References 75 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Unfortunately, direct nitration is a hazardous and environmentally-unfriendly reaction as it uses large excesses of nitric and sulfuric acids. 237,246 …”

Section: N–o Bond Forming Enzymesmentioning

confidence: 99%

Heteroatom–Heteroatom Bond Formation in Natural Product Biosynthesis

et al. 2017

View full text Add to dashboard Cite

Natural products that contain functional groups with heteroatom-heteroatom linkages (X–X, where X = N, O, S, and P) are a small yet intriguing group of metabolites. The reactivity and diversity of these structural motifs has captured the interest of synthetic and biological chemists alike. Functional groups containing X–X bonds are found in all major classes of natural products and often impart significant biological activity. This review presents our current understanding of the biosynthetic logic and enzymatic chemistry involved in the construction of X–X bond containing functional groups within natural products. Elucidating and characterizing biosynthetic pathways that generate X–X bonds could both provide tools for biocatalysis and synthetic biology, as well as guide efforts to uncover new natural products containing these structural features.

show abstract

“…Unfortunately, direct nitration is a hazardous and environmentally-unfriendly reaction as it uses large excesses of nitric and sulfuric acids. 237,246 …”

Section: N–o Bond Forming Enzymesmentioning

confidence: 99%

Heteroatom–Heteroatom Bond Formation in Natural Product Biosynthesis

et al. 2017

View full text Add to dashboard Cite

show abstract

“…These large-scale manufacturingp rocesses, in which hazardous chemicals and for chromatography, [31] and as ac onvenient medium for the environmentally friendly preparationo fc hemical compounds and materials. [58] Application of ILs in aromatic nitration [59] and the use of scCO 2 in the processing of energetic materials [60] are partlyr eviewed. The global concern with regard to environmental safety in differenti ndustrial areas also affected the production of highenergy materials (HEMs).…”

Section: Introductionmentioning

confidence: 99%

“…Significant attentioni sp aid to SCF-basedm icronization techniques that improvet he energetic performanceo fH EMs significantly through the efficient control of the morphology and particle size distribution of the HEM fine particles without degradation or contamination of products. [58] Application of ILs in aromatic nitration [59] and the use of scCO 2 in the processing of energetic materials [60] are partlyr eviewed. However,t ot he best of our knowledge, no comprehensivei nterdisciplinary review covering all these aspects of the synthesis and modification (micronization) of HEMs using ILs and sub-or supercritical fluids has been published so far.…”

Section: Introductionmentioning

confidence: 99%

Prospective Symbiosis of Green Chemistry and Energetic Materials

et al. 2017

View full text Add to dashboard Cite

A global increase in environmental pollution demands the development of new "cleaner" chemical processes. Among urgent improvements, the replacement of traditional hydrocarbon-derived toxic organic solvents with neoteric solvents less harmful for the environment is one of the most vital issues. As a result of the favorable combination of their unique properties, ionic liquids (ILs), dense gases, and supercritical fluids (SCFs) have gained considerable attention as suitable green chemistry media for the preparation and modification of important chemical compounds and materials. In particular, they have a significant potential in a specific and very important area of research associated with the manufacture and processing of high-energy materials (HEMs). These large-scale manufacturing processes, in which hazardous chemicals and extreme conditions are used, produce a huge amount of hard-to-dispose-of waste. Furthermore, they are risky to staff, and any improvements that would reduce the fire and explosion risks of the corresponding processes are highly desirable. In this Review, useful applications of almost nonflammable ILs, dense gases, and SCFs (first of all, CO ) for nitration and other reactions used for manufacturing HEMs are considered. Recent advances in the field of energetic (oxygen-balanced and hypergolic) ILs are summarized. Significant attention is paid to the SCF-based micronization techniques, which improve the energetic performance of HEMs through an efficient control of the morphology and particle size distribution of the HEM fine particles, and to useful applications of SCFs in HEM processing that makes them less hazardous.

show abstract

“…A large number of modified nitrating reagents and catalysts have been developed to avoid release of excess acid waste streams, use of excessive reagents, over‐nitration, oxidative side products and safety problems of common nitrating agents involving mixtures of concentrated or fuming nitric acid with sulfuric acid . The modified nitration methods have been reported to utilize ionic liquids, superacids, alkyl nitrates, nitronium salts or metal nitrates, supported catalysts, etc. In these reports, ionic liquids acted as better reaction media in the presence of concentrated nitric acid …”

Section: Introductionmentioning

confidence: 99%

2‐Methyl‐1,3‐disulfoimidazolium polyoxometalate hybrid catalytic systems as equivalent safer alternatives to concentrated sulfuric acid in nitration of aromatic compounds

Saikia

Borah

2019

Applied Organom Chemis

View full text Add to dashboard Cite

Ionic liquid‐derived polyoxometalate salts [mdsim]3[PM12O40] (where M = W and Mo) of two heteropolyacids H3PW12O40.nH2O and H3PMo12O40.nH2O were synthesized using 2‐methyl‐1,3‐disulfoimidazolium chloride ([mdsim][Cl]) ionic liquid and the corresponding heteropolyacids. Three equivalents of [mdsim][Cl] were treated with the respective Keggin‐structured heteropolyacids (one equivalent) in aqueous medium at room temperature to afford the water‐stable ionic polyoxometalates as acidic solids. They were completely characterized using spectroscopic and other analytical techniques including thermal analysis and Hammett acidity studies. The inherent Brønsted acidic properties of ─SO3H group of these polyoxometalate salts were studied for the nitration of aromatic compounds with 69% HNO3 at normal temperature and 80°C without use of any external concentrated sulfuric acid. These strongly acidic polyoxometalates display good recyclability and efficient reusability.

show abstract

Review on Greener and Safer Synthesis of Nitro Compounds

Cited by 36 publications

References 75 publications

Heteroatom–Heteroatom Bond Formation in Natural Product Biosynthesis

Heteroatom–Heteroatom Bond Formation in Natural Product Biosynthesis

Prospective Symbiosis of Green Chemistry and Energetic Materials

2‐Methyl‐1,3‐disulfoimidazolium polyoxometalate hybrid catalytic systems as equivalent safer alternatives to concentrated sulfuric acid in nitration of aromatic compounds

Contact Info

Product

Resources

About