Review of the genus Ipomoea: traditional uses, chemistry and biological activities

Abstract

Approximately 600-700 species of Ipomoea, Convolvulaceae, are found throughout tropical and subtropical regions of the world. Several of those species have been used as ornamental plants, food, medicines or in religious ritual. The present work reviews the traditional uses, chemistry and biological activities of Ipomoea species and illustrates the potential of the genus as a source of therapeutic agents. These species are used in different parts of the world for the treatment of several diseases, such as, diabetes, hypertension, dysentery, constipation, fatigue, arthritis, rheumatism, hydrocephaly, meningitis, kidney ailments and infl ammations. Some of these species showed antimicrobial, analgesic, spasmolitic, spasmogenic, hypoglycemic, hypotensive, anticoagulant, anti-infl ammatory, psychotomimetic and anticancer activities. Alkaloids, phenolics compounds and glycolipids are the most common biologically active constituents from these plant extracts.

Bioinformatics: Inflammatory Cytokines and Attenuation of Diabetes Hypercholesterolemia-Induced Renal Injury Using Morning Glory and Necklace Pod Extracts

“…The leaves extract purple I. batatas showed inhibitive effect on cell adhesion and inflammatory mediation in endothelial cells of human aorta [24]. Hence; it is probable that the enhancement of endothelial dysfunction effect of MGE may be referred to its bioactive phenolic secondary metabolites as anthocyanins, flavonoids, and other flavonoids derivatives content [7].…”

“…Genus Ipomoea has different secondary metabolites of variable activity [7]. Several phenolic compounds, namely, phenolic acids, flavonoids, and organic acids have been described in several Ipomoea species [10,23].…”

“…The genera of Sophora and Ipomoea are a prolific source of structurally diverse bioactive metabolites with interesting activities [6,7]. The chemical review on necklace pod ([NP], Sophora tomentosa, reveals the presence of alkaloids, polysaccharides, isoprenylated flavonoids, isoflavonones, flavones, flavonols, and their glycosides.…”

“…Many phytochemical studies [7], declared that Ipomoea contains many bioactive secondary metabolites, such as phenolic acids, flavonoids, organic acids, and anthocyanins, with promising effects in ameliorating different disorders such as antinociceptive, antioxidative, and antiinflammatory effects. The isolated anthocyanins decreased the atherosclerotic progress, ameliorated oxidative stress and endothelial dysfunction in mice [10].…”

Diversidade e estrutura genética de populações de batata da serra (<i>Ipomoea serrana</i> Sim.-Bianch. &amp; L.V. Vasconcelos) da Chapada Diamantina, Bahia, utilizando marcadores ISSR

“…Trata-se de um gênero com espécies de grande relevância para a economia englobando alimentícias, ornamentais, medicinais, agrícolas (FERREIRA, 2009;ISLAM, 2006;LORENZI, 1991;MEIRA et al, 2012;MOHANRAJ;SIVASANKAR, 2014;XAVIER et al, 2015), bem como matéria prima para produção de bioetanol (WALUYO et al, 2015), dentre as quais a I. batatas (L.) Lam. (batata doce) tem tido destaque como objeto de estudos 23 (KHOURY et al, 2015;NASCIMENTO K.O et al, 2013;VEASEY et al, 2007;ZAWEDDE et al, 2014), com destaque para estudos moleculares na subseção 2.6 deste trabalho.…”