2012
DOI: 10.1093/eurheartj/ehs347
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Review of surgical prosthetic paravalvular leaks: diagnosis and catheter-based closure

Abstract: Paravalvular leak (PVL) is an uncommon yet serious complication associated with surgical prosthetic valve implantation. Paravalvular leak can have significant clinical consequence such as congestive heart failure, haemolytic anaemia, and infective endocarditis. Recently, transcatheter therapy has been applied to the treatment of this disorder with reasonable procedural and clinical success. This review discusses the current state of PVLs, the utilization of multi-modality imaging in their diagnosis and treatme… Show more

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Cited by 161 publications
(144 citation statements)
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“…Surgical intervention to repair the leak improves symptoms of congestive heart failure, augments the hematocrit value, decreases the need for blood transfusion, and is an independent predictor of long-term survival when compared with medical therapy. Choice of operation involves either direct suture repair of the leak site, which carries a failure rate of 13%; or replacement of the valve, which carries a failure rate of up to 35% (21). In our study group of 47 patients we preferred to have direct suture repair in 28 patients (59.6%) and failure was observed in 1 patient (3.57%) however, and 19 patients (40.4%) underwent re-replacement and the failure was observed in 1 patients (5.26%) and there is no difference between the failure rates of the two groups.…”
Section: Discussionmentioning
confidence: 99%
“…Surgical intervention to repair the leak improves symptoms of congestive heart failure, augments the hematocrit value, decreases the need for blood transfusion, and is an independent predictor of long-term survival when compared with medical therapy. Choice of operation involves either direct suture repair of the leak site, which carries a failure rate of 13%; or replacement of the valve, which carries a failure rate of up to 35% (21). In our study group of 47 patients we preferred to have direct suture repair in 28 patients (59.6%) and failure was observed in 1 patient (3.57%) however, and 19 patients (40.4%) underwent re-replacement and the failure was observed in 1 patients (5.26%) and there is no difference between the failure rates of the two groups.…”
Section: Discussionmentioning
confidence: 99%
“…Hourihan performed the first reported transcatheter closure of PVL in 1992 with double umbrella device and since then the technique is considerably developed [3]. Percutaneous PVL closure has been shown to be safe and effective treatment in different series [4,[5][6][7].…”
Section: Discussionmentioning
confidence: 99%
“…Known risk factors for PVL occurrence include annular calcification, small prosthetic size, inadequate suturing technique, and infection [15]. PVLs that are identified soon after implantations are most often secondary to technical complications of the operation; in contrast, PVLs identified late after surgery are most frequently a consequence of infectious endocarditis or secondary to significant annular calcification [16].…”
Section: Etiology and Natural Historymentioning
confidence: 99%