Review of 346 patients with free-flap reconstruction following head and neck surgery for neoplasm

Podrecca, S.; Salvatori, P.; Saraceno, Massimo Squadrelli; D, Fallahdar; Calabrese, Luca; Cantù, Giulio; Molinari, Roberto

doi:10.1016/j.bjps.2005.08.002

Cited by 45 publications

(45 citation statements)

References 17 publications

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“…In our series, the total perioperative mortality and postoperative morbidity rates of the operative procedures were 6.7 and 20.2 %, respectively, which compare favorably with the results of others [4,10,11,[15][16][17]. There was no significant difference between the three groups regarding mortality and morbidity.…”

Section: Discussionsupporting

confidence: 85%

“…Local skin flaps and deltopectoral flaps are rarely used because of the need for multistage procedures; the limited length of potential reconstruction and high morbidity rates resulting from fistula formation, stricture, and flap necrosis [8,9]. The use of tubed FCFF has been increasing as series reporting outcomes superior or equivalent to JFFs are published [10,11].…”

Section: Discussionmentioning

confidence: 99%

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Hypopharyngeal reconstruction: a comparison of three alternatives

Elfeky

Nasr

Khazbak

et al. 2014

Eur Arch Otorhinolaryngol

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This study aimed to evaluate the operative outcomes of using gastric pull-up (GPU), pectoralis major myocutaneous flap (PMMF), and jejunal free flap (JFF) to reconstruct the hypopharynx after resection of hypopharyngeal and cervical esophageal carcinoma. Retrospective clinical study. Otolaryngology Department, Zagazig University Hospital, Egypt and Surgical Department, National Cancer Institute, Cairo, Egypt. Records of 104 patients who underwent resection of carcinoma of the hypopharynx and cervical esophagus were reviewed to determine the indications for radical resection, location, and stage of the primary tumor, gross and pathological surgical resection margins, operative complications, morbidity, and mortality. Reconstruction was performed using the GPU for group (1) (n = 33), PMMF for group (2) (n = 34), and JFF for group (3) (n = 37). The hypopharynx was the most common primary tumor site for group (2) and group (3) whereas group (1) had lesions more frequently in the cervical esophagus. The overall postoperative morbidity rate was 20.2% with a perioperative mortality rate of 6.7% and there was no significant difference between the three groups. There was no graft necrosis in group (1) compared to 5.9% in group (2) and 5.4% in group (3). Pulmonary complications occurred commonly (30.3%) in group (1) compared to 11.8% in group (2) and 10.8% in group (3) The overall 3 years survival rate was 67.3% and there was no significant difference between the three groups. The outcomes of the three techniques are equally successful when used appropriately. The nature of the defect indicates the method of reconstruction. For short reconstruction above the thoracic inlet, PMMF or JFF are equally effective and in tumors requiring total esophagectomy, GPA is indicated.

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Section: Discussionsupporting

confidence: 85%

Section: Discussionmentioning

confidence: 99%

Hypopharyngeal reconstruction: a comparison of three alternatives

Elfeky

Nasr

Khazbak

et al. 2014

Eur Arch Otorhinolaryngol

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“…Complication rates were not significantly higher for microvascular free flaps in this series, despite being used for more locoregionally advanced cancers with higher rates of radiation and chemotherapy being given after surgery. Fistula and (14) 50 (14) .97…”

Section: Discussionmentioning

confidence: 99%

Impact of reconstructive microsurgery in patients with advanced oral cavity cancers

et al. 2009

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“…Series of patients submitted to free flap reconstruction focused on showing their survival results without effectively comparing different treatment modalities. The main focus was stating the acceptable survival rates obtained by free flap reconstruction and encouraging their use (Podrecca et al, 2006). These articles presented contradictory results due to different settings, patient selection and statistical analysis.…”

Section: Oncologic Resultsmentioning

confidence: 99%