“…Over 250 ABO alleles were deposited into the database, including alleles specifying A1, A2, A3, Ael, Aint, Am, Aw, Ax, cis -AB, B(A), B (B1), B3, Bel, Bw, Bx, and O phenotypes. Many missense mutations, nonsense mutations, and frameshift mutations (insertions and deletions) identified in the coding sequence of the ABO gene have been extensively reviewed and therefore are not duplicated in this review (see review articles [ 33 , 34 ] for detailed information on individual alleles and their references). Mutations have also been discovered that changed the mRNA splicing pattern of the ABO gene [ 35 – 37 ] or that altered the promoter/enhancer activity in the transcription of the ABO gene [ 31 , 38 , 39 ].…”