Reversed-Phase Ion-Pair Liquid Chromatography of a Pharmaceutical Compound and Its Photolytically Transformed Isomer

Characterization of a novel impurity in bulk drug eprosartan by ESI/MSn and NMR

“…A series of separation and detection techniques have been applied to the analysis of eprosartan, such as high-performance liquid chromatography (HPLC) coupled with ultraviolet (UV) [6] or mass spectrometric method [7], and solid phase extraction-highperformance liquid chromatographic method [8,9]. Most of these methods were used to monitor eprosartan concentration in biological fluids.…”