“…For this reason, different strategies have been proposed, based on the use of delivery devices such as microspheres, microemulsions, nanoparticles, microcapsules, implantable pumps, and vesicular systems among others. [1][2][3][4][5][6][7] There are several advantages of using active compound delivery systems, for example, to protect drugs from a hostile environment (enzymes, pH, heat, air, light, moisture) or to improve poor aqueous solubility of the active agents that limits bioavailability and efficiency in the action site. 8,9 Among the promising drug targeting vehicles are vesicles.…”