Révélation à l’âge adulte d’une sphérocytose héréditaire devant une tumeur rénale : forme frontière entre myélolipome et foyer d’hématopoïèse extra-médullaire

Adrenal extramedullary hematopoiesis associated with beta-thalassemia trait in an adult woman: a case report and review of literature

“…Extramedullary hematopoiesis (EMH) is a physiological compensatory phenomenon in response to altered hematopoiesis occurring secondary to inadequate bone marrow function [1] , [2] , [3] , [4] . It often occurs in hemoglobinopathies, hemolytic anemias, leukemias, lymphomas, and myeloproliferative disorders [5] .…”

“…It often occurs in hemoglobinopathies, hemolytic anemias, leukemias, lymphomas, and myeloproliferative disorders [5] . EMH in the medical literature was commonly found in the liver and spleen whereas it is rarely seen in adrenal glands, breast, dura mater, and bowel [1] , [2] , [3] , [4] . All these extramedullary sites are thought to be engaged in active hematopoiesis in fetal life which normally stops at birth, but can retain this function under long-standing circumstances leading to ineffective red blood cells formation [1] .…”

Rare Presentation of Right Adrenal Mass: Extramedullary Haematopoiesis in a Patient with Thalassaemia Intermedia

“…EMH in the medical literature was commonly found in the liver and spleen whereas it is rarely seen in adrenal glands, breast, dura mater, and bowel. 5,[7][8][9] It often occurs in hemoglobinopathies, hemolytic anemias and myeloproliferative disorders. 10 Pathological causes of EMH in the adrenal gland were described in multiple case reports, which included the defects in hemoglobin production associated with sicklecell disease, 9 hemoglobin H constant spring disease, 11 thalassemia 8,12-16 and impaired red blood cell membrane production linked with hereditary spherocytosis.…”

Développement d'un sarcome sur foyer ectopique hématopoïétique secondaire à une sphérocytose héréditaire : à propos d'un cas et revue de la littérature

“…Le rehaussement par un produit de contraste est inconstant [15]. La TEPscanner montre un métabolisme dépendant de l'activité hématopoïétique, en général faible [17,18]. Deux traceurs ont montré leur utilité pour explorer les anomalies de la moelle osseuse et notamment dans la localisation d'HEM : ainsi, le FDG montrant l'hypermétabolisme glucique, et le 3'-18F-fluoro-3'-deoxy-Lthymidine (FLT) montrant la synthèse d'ADN [19].…”