2019
DOI: 10.1002/ccr3.2614
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Revascularization and vital pulp therapy in immature molars with necrotic pulp and irreversible pulpitis: A case report with two‐year follow‐up

Abstract: Management of teeth with inflamed pulp has been always a challenge.Revascularization and vital pulp therapy are suggested as procedures for successful treatment of immature molars diagnosed with pulp necrosis and irreversible pulpitis, respectively. K E Y W O R D Simmature tooth, regenerative endodontics, revascularization, vital pulp therapy How to cite this article: Ramezani M, Sanaei-rad P, Hajihassani N. Revascularization and vital pulp therapy in immature molars with necrotic pulp and irreversible pulpiti… Show more

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Cited by 7 publications
(6 citation statements)
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“…This article presented a case report on failed regenerative endodontic treatment and its clinical management. Although the success of regenerative endodontic procedures (REPs) was highly reported in the literature [11][12][13][14][15][16][17][18][19][20][21] , few cases described unfavorable outcomes and their further management 8,9,10 . The success of regenerative endodontic procedures (REPs) is governed by the stage of root maturation 5,22 , the size of the apical diameter 5,23,24 , the cytotoxicity of the root canal irrigants, the antimicrobial efficacy of the intracanal medicament, and the long-standing nature of the preceding infection 5 .…”
Section: Discussionmentioning
confidence: 99%
“…This article presented a case report on failed regenerative endodontic treatment and its clinical management. Although the success of regenerative endodontic procedures (REPs) was highly reported in the literature [11][12][13][14][15][16][17][18][19][20][21] , few cases described unfavorable outcomes and their further management 8,9,10 . The success of regenerative endodontic procedures (REPs) is governed by the stage of root maturation 5,22 , the size of the apical diameter 5,23,24 , the cytotoxicity of the root canal irrigants, the antimicrobial efficacy of the intracanal medicament, and the long-standing nature of the preceding infection 5 .…”
Section: Discussionmentioning
confidence: 99%
“…Conventional endodontic treatment consists in the development and application of techniques aimed at performing chemical-mechanical preparation of root canals in order to eliminate an infection, often difficult to fight due to the complexity of the root canal system (Araújo, 2017;Hameed, 2019;Ramezani, 2019;Xie, 2021). However, this process can become even more complicated in cases of immature teeth with open apexes, whose root walls are fragile due to the thin thickness of the dentin of the root canal, combined with the intense activity and anatomy of an open apex, hindering the complete filling of the root canal, and with risk of extravasation of solid and plastic material to the periapex (Faria, 2019;Nosrat et al, 2019;Nicoloso, 2019).…”
Section: Introductionmentioning
confidence: 99%
“…Pulp revascularization has been consolidated as a viable and effective alternative for the treatment of immature necrotic teeth (El-Tayeb, 2019;Nageh, 2018;Parhizkar, 2018;Yang, 2022). It presents advantages over conventional techniques, such as the possibility of continuous root development and the consequent strengthening of dental structure (Glynis, 2022;He, 2022;Ramezani, 2019). Its steps involve decontamination with root canal irrigators, insertion of intracanal medication, induction of blood clots, and coronary sealing (Montero-Miranelles, 2018).…”
Section: Introductionmentioning
confidence: 99%
“…REPs have emerged as a new therapeutic modality for immature permanent teeth based on regenerative medicine [4]. One of the successful REPs is the cell‐free approach, in which bleeding is induced and the resulting blood clots create a scaffold for the mesenchymal stem cells (MSCs) to proliferate and differentiate into the vital components of the pulp–dentin complex [5]. With REPs, the root continues its development, and the dentin wall thickens, in addition to the revitalisation of the pulp tissue with the potential to regain nociception and immune competence [6].…”
Section: Introductionmentioning
confidence: 99%