Return to fertility after removal of a levonorgestrel-releasing intrauterine device and Nova-T

The non-contraceptive effects of the levonorgestrel-releasing intrauterine device

“…A few other clinical trials with smaller study populations have been reported from China comparing the IUD that releases 2/zg of levonorgestrel daily (LNG-IUD-02) with IUDs made in China [17,18], or the LNG-IUD-20 with Norplant implants [19,20]. Other aspects of the LNG-IUD-20, like return of fertility [15,[21][22][23], use by postpartum and/or lactating women [24,25], or using the LNG-IUD-20 as a treatment for menorrhagia or dysmenorrhea [13,[26][27][28][29], have been reported sporadically, mostly by Scandinavian or British investigators.…”

“…In the European Study [22], 79.1 per 100 LNG-IUD-20 users and 71.2 per 100 Nova-T users became pregnant within 12 months after removal. The Population Council Study [15,23] showed that return of fertility in LNG-IUD-20 users after removal was as rapid as in women discontinuing use of the copper-releasing IUDs.…”

Return to fertility following discontinuation of oral contraceptives

“…In aggregate conception rates at 12 months following discontinuation of cyclic OCs (21 days of active hormone pills followed by 7 days of placebo pills) in women wishing to conceive range from 72%-94% (1, 2, 17, 22-25; Table 1). In comparison, published 12-month conception rates are 75%-79% in women stopping the levonorgestrel (LNG) IUD (26)(27)(28) and 71% to 92% in women stopping the copper IUD (28)(29)(30)(31)(32)(33)(34) in order to conceive.…”

“…The figure provides the range of 12-month conception rates reported in women stopping various methods of contraception (1,2,17,(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)49). OC, oral contraceptive; Cu, copper; IUD, intrauterine device; LNG, levonorgestrel; DMPA, depot medroxyprogestrone acetate; POP, progesterone-only pill.…”

Three-year efficacy and safety of a new 52-mg levonorgestrel-releasing intrauterine system

“…Intrauterine contraceptives can prevent pregnancy for several years, with efficacy equivalent to contraceptive sterilization [5]. When intrauterine contraceptives are removed, the return to fertility is rapid [6][7][8].…”