Retroviral origins of the<i>Caenorhabditis elegans</i>orphan gene F58H7.5

Wj, Kapulkin

doi:10.1101/073510

Cited by 3 publications

(1 citation statement)

References 36 publications

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“…canephora Protects plants against drought [27] Xio1 Oryza Triggers enhance resistance to Xanthomonas oryzae pv. oryzae in rice [28] Tssor-3 and Tssor-4 Plutella xylostella Role in male fertility in P. xylostella [29] MoSPC1, MoSPC2, MoSPC3 and MoSPC7 Magnaporthe oryzae Species-specific adaptive processes [30] CcUnk Coffee Involved in abiotic and biotic stress responses [31] Ms2 Wheat For recurrent selection and hybrid seed production in wheat [32] IAPAR59 Coffee Drought tolerance in coffee [33] TaSnRK1αs Wheat Contributes positively to wheat tolerance of DON [34] F58H7.5 C. elegans Involved as RNA intermediate [35] Pf-5 Pseudomonas fluorescens Produces six secondary metabolites [36] nog1…”

Section: Ccunk8mentioning

confidence: 99%

The Lost and Found: Unraveling the Functions of Orphan Genes

Fakhar

Liu

Pajerowska-Mukhtar

et al. 2023

JDB

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Orphan Genes (OGs) are a mysterious class of genes that have recently gained significant attention. Despite lacking a clear evolutionary history, they are found in nearly all living organisms, from bacteria to humans, and they play important roles in diverse biological processes. The discovery of OGs was first made through comparative genomics followed by the identification of unique genes across different species. OGs tend to be more prevalent in species with larger genomes, such as plants and animals, and their evolutionary origins remain unclear but potentially arise from gene duplication, horizontal gene transfer (HGT), or de novo origination. Although their precise function is not well understood, OGs have been implicated in crucial biological processes such as development, metabolism, and stress responses. To better understand their significance, researchers are using a variety of approaches, including transcriptomics, functional genomics, and molecular biology. This review offers a comprehensive overview of the current knowledge of OGs in all domains of life, highlighting the possible role of dark transcriptomics in their evolution. More research is needed to fully comprehend the role of OGs in biology and their impact on various biological processes.

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