Retroperitoneal liposarcoma extending into the thigh

Giant Atypical Spindle Cell Lipomatous Tumor of Retroperitoneal Origin Presenting with Lung Metastasis and Extension to the Thigh: A Case Report with Literature Review

“…5 Distant metastasis is infrequent, observed in 5% patients, while the local disease is mostly associated with mortality. 9 In addition to abdominopelvic swelling, our patient had respiratory complaints, and thus CECT chest was performed, resulting in diagnosis of lung metastasis.…”

“…To achieve complete resection of the tumor, 57 to 77% patients require resection of adjacent structures. 9 However, recurrence of sarcoma following primary surgical resection is a constant issue. Around 69 to 80% patients with first recurrence tend to have multiple local recurrences.…”

“…12 The chances of local recurrence are reduced, and survival is improved in patients with low-grade tumors and macroscopic clearance. 9 Neoadjuvant therapies (chemotherapy, radiotherapy, or their combination) are safe in well-selected patients, and may be considered only after a careful review. In our patient, owing to giant size of ASCLT, neoadjuvant chemoradiotherapy was initiated with an aim to shrink the tumor size.…”

“…5 Computed tomography (CT) of the abdomen and pelvis as well as thorax is sufficient to reach the diagnosis, and assess the distant metastasis, respectively. Though literature suggests extension of RP LS to thigh, 9 10 extension of ASCLT to thigh has not been reported yet. Herein, we present a case of giant metastatic ASCLT originating from the RP region in a young male.…”

Massive dedifferentiated thigh liposarcoma growing for 10 years and extending into the retroperitoneum: a case report

“…In this report, we are presenting the case of a female patient with a massive dedifferentiated liposarcoma of the thigh that was growing for 10 years and, subsequently, spread to the retroperitoneum. By reviewing the literature, we found a similar case report describing a massive, initially retroperitoneal, dedifferentiated liposarcoma which spread to other anatomical regions [ 13 ], but we did not find any case reports describing dedifferentiated liposarcoma of the upper leg that was growing for 10 years and spread through the inguinal canal into the retroperitoneum. Due to the specificity of the case, a new, specific surgical technique was used.…”