Retroperitoneal Fibrosis in a Patient with Gastric Cancer Manifested by Lower Extremity Edema and Hydrocele

Abstract

Herein we report a 57-year-old man with lower extremity edema and swelling in the scrotum who was found to have a periaortic soft tissue mass and hydronephrosis by computed tomography. With the most plausible diagnosis of retroperitoneal fibrosis, corticosteroid therapy was initiated; however, it did not improve his symptoms. Upper gastroscopy performed on day 20 post admission showed ulcerative regions with an irregular border and fusion of thickened rugae at the gastric angle; the diagnosis of gastric adenocarcinoma was confirmed histologically. It is important to always be aware of unrecognized malignancies that are accompanied by retroperitoneal fibrosis.

Retroperitoneal Fibrosis Due to Opium Abuse: A Case Series and Literature Review

“…RPF has an unclear etiology, and was first described by Albarron in 1905 (1, 2). However, more cases of this disease have since been reported (1, 7, 8). RPF is also known as Ormond’s disease (9).…”

Fibrosis retroperitoneal asociada a neoplasias malignas: Serie de casos clínicos

“…Fibrosis retroperitoneal y cáncer -J. Vega et al tumores carcinoides, linfomas, mieloma múltiple y sarcomas 7,9,[14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29] . Las asociaciones con tumores benignos son menos frecuentes (angiomiolipomas renales, ganglioneuromas, tumores del aparato yuxtaglomerular) [30][31][32] .…”

“…A la fecha de corte de nuestro estudio (diciembre de 2013) 3 de ellos se encontraban en remisión clínica, 1 tenía evidencias de enfermedad metastásica y 2 habían fallecido (progresión del cáncer, sepsis). La falta de respuesta a los corticoides en una FRPI debe hacer sospechar la presencia de una FRPM, como ocurrió en una de nuestras pacientes (caso 5) y debe buscarse un tumor 14 .…”

Retroperitoneal Fibrosis in a Chinese Woman with Systemic Lupus Erythematosus: A Case Report

“…Patient was followed in clinic for about one year and repeat CT, patients with RPF. Some patients also manifest with edema, such as lower extremity edema [8], or scrotum edema [9] and even cerebral edema. The general symptoms include anorexia, fatigue, weight loss, etc.…”