The present research is the first to assess fracture of V-notches with end holes (VOnotches) made of tungsten-copper functionally graded material (W-Cu FGM) under mode I both experimentally and theoretically. W-Cu FGM specimens were fabricated by powder metallurgy technique. A number of fracture tests were carried out on VOnotched W-Cu FGM specimens under mode I for various notch tip radii, notch depths, and notch opening angles.The averaged strain energy density over a well-defined control volume was employed to predict the fracture loads. A numerical approach was used to determine the outer boundary of the control volume. Besides, the effect of notch geometry (notch tip radius, notch depth, and notch opening angle) on fracture load was elaborated. This study demonstrates that SED works well on VO-notched FGM specimens under mode I loading.