Retracted Article: Polycaprolactone composites with TiO₂ for potential nanobiomaterials: tunable properties using different phases

Abstract

TiO(2) nanoparticles of different phases play a key role in property alteration of nanocomposite fibers. Polycaprolactone (PCL)/TiO(2) composite fibers were prepared using the electrospinning method. Pure anatase and rutile phases were synthesized using the sol-gel route for nanocomposite synthesis. The Effect of nanoparticle phases on crystallinity of fibers and interaction with polymer molecules have been studied using X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, Raman spectroscopy, morphology through SEM, surface properties using BET method and wetting property of fibers commencing from contact angle measurement. Biocompatibility and biodegradation of hybrid materials have been studied in simulated body fluid (SBF) and phosphate buffer (PBS), respectively. The anatase phase with smaller particle dimensions exhibited significant improvement of most of the properties as compared to composites made of the rutile phase. Better interaction between polymer chain and anatase particle PCL-A nanocomposite fibers leads to better mechanical property and biocompatibility vis-à-vis PCL-R and pristine PCL fibers. Biocompatibility of PCL nanocomposite has been testified through proliferation of fibroblast cell and its adhesion; MTT (3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay demonstrates good proliferation rate for cells on PCL-A nanocomposite fibres.

Making Nonwoven Fibrous Poly(ε‐caprolactone) Constructs for Antimicrobial and Tissue Engineering Applications by Pressurized Melt Gyration

“…The intensity and the sharpness of the peaks increased with temperature, which is attributed to increase in crystallinity in the PCL scaffolds generated. The peaks at 1438, 1308, 1107, and 912 cm −1 correspond to (δCH 2 ), (wCH 2 ) bonding, skeletal stretching, and νCCOO bonding, respectively, and belong to crystalline phases . The peak obtained between 1720–1739 cm −1 is assigned to CO stretching vibration .…”

3D Printed Polycaprolactone Carbon Nanotube Composite Scaffolds for Cardiac Tissue Engineering

“…The disordered graphite structure or sp 3 ‐hybridized carbons of the CNT is demarcated by the peak at 1350 cm −1 also known as D‐band, while the structural intensity of sp 2 ‐hybridized carbon atoms or tangential mode is assigned to peak at 1580 cm −1 (G‐band). The Raman spectrum of PCL shows the characteristic peaks at 1723 cm −1 (νCO), 1040–1106 cm −1 (skeletal vibration), 1470–1415 cm −1 (δCH 2 ), and 1281–1305 cm −1 (wCH 2 ) attributable to CH 2 groups . Both characteristic bands (D and G) are absent in pure PCL.…”

“…PCL nanocomposites (nanoclays, graphene, and CNTs) can be prepared using methods such as solvent casting, freeze drying, and electrospinning . However, these existing fabrication methods are unable to produce scaffolds of desired control pore sizes.…”

Comparative study of the effects of anatase and rutile titanium dioxide nanoparticles on the structure and properties of waterborne polyurethane

“…This reinforcement is influenced by the factors like particle size, particle shape and specific surface area. For example, the anatase TiO 2 with smaller particle dimensions exhibited significant improvement of mechanical properties of polycaprolactone/TiO 2 composites compared to the composites made of the rutile TiO 2 [18].…”