Retinoic Acid Treatment of Nipple Hyperkeratosis

Pérez-Izquierdo, José M.; Vilata, J.J.; Sánchez, Jorge; Gargallo, E.; Millán, Fernando; Aliaga, A

doi:10.1001/archderm.1990.01670290135032

Cited by 46 publications

(35 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Perez-Izquierdo suggested an alternative classification of two types: idiopathic or nevoid, which may be unilateral or bilateral. Other type is secondary to local lesions like verrucous nevus or seborrheic keratosis; or associated with other diseases which include ichthyosis, Darier's disease, acanthosis nigricans chronic eczema, lymphomas, or drug related e.g., diethylstilbestrol and spironolactone [5]. Mehanna et al suggested that the term ‚nevoid' be replaced by ‚idiopathic' [6].…”

Section: Discussionmentioning

confidence: 99%

Hyperkeratosis of nipple and areola

Ambika¹,

Chankramath²

2012

Our Dermatol Online

View full text Add to dashboard Cite

A 26 year old pregnant female presented with verrucous lesion on nipple and areola of 10 year duration. Histopathology of lesion was consistent with benign pappiloma, which can occur with various clinical differential dignosis which cause clinical picture of hyperkeratosis of nipple and areola. It can occur as isolated entity which is idiopathic or secondary to various causes like epidermal nevus, seborrhoic keratosis, eczema, icthyosis or acanthosis nigricans. Lesion may increase in size in pregnancy and may cause worry to patient regarding nursing the babies in our case. Lesions was removed by radiofrequency cautery.Streszczenie 26-letnia kobieta w ciąży prezentowała brodawkujące zmiany na brodawce sutka i otoczce trwające 10 lat. Histopatologia zmiany była zgodna z łagodną brodawką, która może służyć do diagnostyki różnicowej różnych obrazów klinicznych o charakterze hiperkeratozy na brodawkach i otoczkach sutka. Może ona występować jako pojedyncza jednostka, która jest idiopatyczna lub wtórna z różnych przyczyn, takich jak znamię naskórkowe, rogowacenie łojotokowe, wyprysk, icthyosis lub rogowacenie ciemne. Zmiana może zwiększyć rozmiar w ciąży i może sprawiać zakłopotanie pacjenta w zakresie opieki nad niemowlęciem, tak jak w naszym przypadku. Zmiany zostały usunięte przez przeskórne przyżeganie.

show abstract

Section: Discussionmentioning

confidence: 99%

Hyperkeratosis of nipple and areola

Ambika¹,

Chankramath²

2012

Our Dermatol Online

View full text Add to dashboard Cite

show abstract

“…Moreover, they are completely benign. Although surgical excision of NHNA lesions has also been suggested as an alternative to medical therapy, 16 its efficacy has not been clarified. Baykal and colleagues suggested that the frequency of the disease might be underestimated because the lesions are generally asymptomatic and thus may not reach medical attention.…”

Section: Discussionmentioning

confidence: 99%

Treatment of Nevoid Hyperkeratosis of the Nipple and Areola Using a Radiofrequency Surgical Unit

Özyazgan

Kontaş²,

Ferahbaş

2005

Dermatologic Surgery

View full text Add to dashboard Cite

BACKGROUND. Nevoid hyperkeratosis of the nipple and areola (NHNA) is a rare condition of unknown etiology. Verrucous thickening and pigmentation of the nipple and areola are the main features of the condition. Different therapeutic options, both medical and surgical, have been described.OBJECTIVE. To use a radiofrequency surgical unit to treat an NHNA case, which was unresponsive to keratolytic therapy. MATERIALS AND METHODS. The lesions of the nipple and areolaswere excised tangentially with a diamond-shaped electrode of a radiofrequency surgical unit under local anesthesia. RESULTS. The patient had a good cosmetic appearance after the treatment, and there was no recurrence at the ninth postoperative month.CONCLUSION. Radiofrequency for tangential excision in the treatment of NHNA lesions that have not responded to medical therapy can be an alternative surgical method.

show abstract

“…Although nevoid hyperkeratosis of the nipple and/or areola can affect both men and women, approximately 80% of cases occur in women 3 . For women, onset usually occurs during the second or third decade of life 4 .…”

Section: Discussionmentioning

confidence: 99%

“…On occasion an affected patient may experience pruritus. The lesions usually do not interfere with breast function, although Perez‐Izquierdo et al 3 . reported one patient with difficulty breast‐feeding.…”

Section: Discussionmentioning

confidence: 99%

Nevoid hyperkeratosis of the nipple and/or areola: a report of two cases and a review of the literature

et al. 2002

View full text Add to dashboard Cite

Nevoid hyperkeratosis of the nipple and/or areola is a rare and idiopathic disorder with fewer than 50 cases reported in the literature. We report two cases, discuss the clinical and histological findings, and review the literature pertaining to its pathogenesis and therapy. It is hoped that, through this report, nevoid hyperkeratosis of the nipple and/or areola becomes a more recognizable and reported entity, thereby stimulating future studies regarding its pathogenesis and therapy.

show abstract

Retinoic Acid Treatment of Nipple Hyperkeratosis

Cited by 46 publications

References 2 publications

Hyperkeratosis of nipple and areola

Hyperkeratosis of nipple and areola

Treatment of Nevoid Hyperkeratosis of the Nipple and Areola Using a Radiofrequency Surgical Unit

Nevoid hyperkeratosis of the nipple and/or areola: a report of two cases and a review of the literature

Contact Info

Product

Resources

About