Retinal granuloma caused by Sporothrix schenckii

Curi, André Luiz Land; Félix, Sebastião; Azevedo, Kátia Martins Lopes de; Estrela, Rogério; Villar, Enoí G.; Saraça, Giani

doi:10.1016/s0002-9394(03)00083-7

Cited by 34 publications

(27 citation statements)

References 5 publications

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“…Administration of topical fluconazole may have influenced the results of the culture from the second biopsy. Culture of ocular sporotrichosis is known to sometimes be unsuccessful, 1,3,8,9,11,15,16 and the absence of culture results in our case therefore did not rule out the possibility of conjunctival sporotrichosis. The diagnosis of cutaneous sporotrichosis is made on the basis of its cutaneous appearance and pathologic findings 17,18 and culture analyses are not routinely performed.…”

Section: Discussionmentioning

confidence: 56%

“…Ocular sporotrichosis has previously been reported in various regions, including the eyelids and palpebral conjunctiva, and can present as iridocyclitis, endophthalmitis, and retinal granuloma. [1][2][3][4][5][6][7][8][9] However, reports on bulbar conjunctival sporotrichosis are very rare. 2,4 In addition, the reported cases of conjunctival sporotrichosis failed to describe detailed findings and no report has described the development of a salmon-pink tumor.…”

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confidence: 99%

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Bulbar Conjunctival Sporotrichosis Presenting as a Salmon-Pink Tumor

Kashima

Honma

Kishi

et al. 2010

Cornea

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Section: Discussionmentioning

confidence: 56%

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confidence: 99%

Bulbar Conjunctival Sporotrichosis Presenting as a Salmon-Pink Tumor

Kashima

Honma

Kishi

et al. 2010

Cornea

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“…Disseminated sporotrichosis cases have shown meningeal, respiratory, osteoarticular, lymphatic, and ocular involvement in both HIV-infected and non-HIV patients 14,[20][21][22][23] ; however, endocarditis involvement was not reported to date.…”

Section: Discussionmentioning

confidence: 99%

“…Our patient's ocular infection probably originated from hematogenous spread, although no fungus was recovered from blood cultures. 23,27 Fungal endocarditis accounts for 1.3-6% of all infectious endocarditis cases. These are commonly severe, leading to high morbidity and mortality.…”

Section: Discussionmentioning

confidence: 99%

Disseminated Sporothrix brasiliensis Infection with Endocardial and Ocular Involvement in an HIV-Infected Patient

Silva‐Vergara

Camargo²,

Silva³

et al. 2012

The American Society of Tropical Medicine and Hygiene

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Abstract. Disseminated sporotrichosis occurs in individuals with impaired cellular immunity, such as in cases of neoplasia, transplantation, diabetes, and especially, acquired immunodeficiency syndrome. This report presents a 32-year-old Brazilian human immunodeficiency virus (HIV)-infected patient who developed a protracted condition of disseminated sporotrichosis with endocarditis, bilateral endophthalmitis, and lymphatic involvement. He needed cardiac surgery to replace the mitral valve. Sporothrix brasiliensis isolates were recovered from cultures of subcutaneous nodules and mitral valve fragments. Species identification was based on classical and molecular methods. The patient received amphotericin B for 52 days and subsequently, oral itraconazole. He remains asymptomatic, and he is on maintenance therapy with itraconazole. Despite his positive clinical outcome, he developed bilateral blindness. To our knowledge, this case is the first report of endocarditis and endophthalmitis caused by S. brasiliensis.

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“…Bacterial infection by Treponema pallidum , Bartonella henselae ,3 Mycobacterium tuberculosis 4 and very rarely Streptococcus pyogenes 5 or fungus such as Sporothrix schenckii 6 and Candida albicans 7 or parasite such as Ascarids especially in children8 may produce a granuloma.…”

Section: Discussionmentioning

confidence: 99%

Choroidoretinal granuloma in a young female patient

et al. 2014

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A 16-year-old Brazilian female patient presented with blurring of vision in the right eye. Corrected visual acuity was OD 2/20, OS 20/20. Afferent pupillary defect was absent and anterior segment examination revealed anterior uveitis. Fundus examination showed light vitritis and a raised grey-white granuloma located at posterior pole with focal serous retinal detachment on optical coherence. Indocyacnine green angiography disclosed a complete mask effect in granuloma's area. Differential diagnoses were infectious (bacterial, viral, fungal and parasites) diseases, systemic inflammatory diseases, tumours. Blood serologies (HIV, toxoplasma, Borrelia, cytomegalovirus (CMV), herpes simplex virus (HSV), varicella-zoster virus (VZV), rubeola) showed positive results for IgM and IgG for toxoplasma, and anterior chamber tap (PCR for toxoplasma, CMV, HSV, VZV) revealed toxoplasma DNA. Anti-toxoplasma therapy, pyrimethamine, sulfadiazine and calcium folinate, was administered immediately. On follow-up granuloma regression was observed, with complete visual restoration. This case demonstrates a clinically challenging posterior pole granuloma

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Retinal granuloma caused by Sporothrix schenckii

Cited by 34 publications

References 5 publications

Bulbar Conjunctival Sporotrichosis Presenting as a Salmon-Pink Tumor

Bulbar Conjunctival Sporotrichosis Presenting as a Salmon-Pink Tumor

Disseminated Sporothrix brasiliensis Infection with Endocardial and Ocular Involvement in an HIV-Infected Patient

Choroidoretinal granuloma in a young female patient

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