“…Therefore, human pluripotent stem cells (hPSCs) represent one of the most promising sources of human RGCs. Recent development of methods guiding the differentiation of hPSCs toward specific retinal lineages, including RGCs, has emerged as a powerful strategy for disease modeling, drug screening, and gene or cell therapy (Llonch et al, 2018;Rabesandratana et al, 2018;Miltner and La Torre, 2019;Ahmad et al, 2020). Previous studies have demonstrated the ability to differentiate RGCs from plated hPSC-derived embryoid bodies (Riazifar et al, 2014;Sluch et al, 2015;Gill et al, 2016;Teotia et al, 2017).…”