Retinal and Choroidal Thickness in Children with Familial Mediterranean Fever

Erdurmuş, Mesut; Bekdaş, Mervan; Demircioğlu, Fatih; Soydan, Adem; Göksügür, Sevil Bilir; Kısmet, Erol

doi:10.3109/09273948.2014.916309

Cited by 29 publications

(16 citation statements)

References 27 publications

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“…Further analysis of the results requested in a letter by Uzun et al 54 revealed no effect of either refractive error or the presence or absence of the M694V mutation. 55 These results were generally consistent with those reported by Erdurmuş et al 61 and were perhaps not unsurprising, given how uncommon retinal findings are in patients with FMF.…”

supporting

confidence: 88%

Uveitis in Children and Adolescents

Cunningham

Smith

Tuğal-Tutkun

et al. 2016

Ocular Immunology and Inflammation

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supporting

confidence: 88%

Uveitis in Children and Adolescents

Cunningham

Smith

Tuğal-Tutkun

et al. 2016

Ocular Immunology and Inflammation

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“…Correlations between the variables were investigated using the Pearson or Spearman correlation coefficient. The choroidal thickness data for healthy subjects in Erdurmus et al's [28] study (352.1 ± 60.0 µm) were used in order to calculate the required sample size to find a subfoveal choroidal thickness difference of 10% between the control group and FMF patients. For this purpose, an α error of 5% and a β error of 20% were used.…”

Section: Methodsmentioning

confidence: 99%

Choroidal Thickness Changes in the Acute Attack Period in Patients with Familial Mediterranean Fever

et al. 2015

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Purpose: The aim of this study was to evaluate choroidal thickness changes during acute attacks of familial Mediterranean fever (FMF). Methods: Fifty patients with FMF and 50 healthy controls were included. Choroidal thickness of each participant was measured at the foveola and horizontal nasal and temporal quadrants at 500-µm intervals to 1,500 µm from the foveola using spectral-domain optical coherence tomography. White blood cell count, erythrocyte sedimentation rate (ESR) and serum levels of fibrinogen and C-reactive protein (CRP) were evaluated. The clinical findings (peritonitis, arthritis and pleuritis) were noted. Results: Choroidal thickness was significantly thicker at all measurement points in FMF patients compared to healthy controls during an acute attack (p < 0.05). There were positive correlations between the choroidal thickness and ESR, fibrinogen and, particularly, CRP levels. Clinical findings did not change the choroidal thickness significantly (p > 0.05). Conclusions: Increased choroidal thickness in the acute phase of FMF is possibly related to the inflammatory edematous changes in the choroid.

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“…We congratulate Erdurmus et al 1 for their study entitled ''Retinal and Choroidal Thickness in Children with Familial Mediterranean Fever.'' The authors found that retinal and choroidal thickness did not differ significantly between familial Mediterrenean fever (FMF) patients and healthy controls.…”

mentioning

confidence: 99%