Retention characteristics of polypyrrole as a stationary phase for the electrochemically modulated liquid chromatographic (EMLC) separations of dansyl amino acids

Deinhammer, Randall S.; Porter, Marc D.; Shimazu, Katsuaki

doi:10.1016/0022-0728(95)03879-l

Cited by 43 publications

(40 citation statements)

References 61 publications

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“…Przybycien also studied the retention change of p-lactoglobulin on the stationary phase of hemeagarose while the redox state of the stationary phase was manipulated by additives to mobile phase [22]. Deinhammer, Shimazu and Porter reported some improvements in the preparations of polypyrrole coating, applying these coatings to separations of adenosine phosphates [23] and amino acids [24]. The latter studies demonstrated for the first time the ability to manipulate retention by changing electrochemically the composition of a stationary phase during analyte elution.…”

Section: Literature Reviewmentioning

confidence: 99%

Electrochemically-modulated liquid chromatography (EMLC): Column design, retention processes, and applications

Ting

1997

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Section: Literature Reviewmentioning

confidence: 99%

Electrochemically-modulated liquid chromatography (EMLC): Column design, retention processes, and applications

Ting

1997

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“…The electrical potential of this stationary phase can be controlled by a potentiostat. The use of charge-controllable stationary phases for chromatographic purposes has been discussed in the literature, especially by Deinhammer et al [5][6][7]. In principle a column with such a stationary phase can be used either for cation-or anion-exchange applications, depending on the electrode potential selected.…”

Section: Introductionmentioning

confidence: 98%

Potential-controlled chromatography for the separation of amino acids and peptides

et al. 2005

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Potential-controlled chromatography is introduced as a new technique for the separation of amino acids and peptides. The principle of potential-controlled chromatography depends on the use of electrically conductive material as the stationary phase of the chromatographic column. Thus from an electrochemical point of view the packed column can be regarded as a packed-bed electrode. The electrical potential of this stationary phase can be controlled by a potentiostat. The separation of amino acid and peptide molecules during their migration through the column depends on their own electric charge on the one hand and on the electrical potential of the stationary phase on the other. The chromatographic separation of some amino acids could be demonstrated.

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“…( Examples include the development of ion-gate membranes, [29][30][31] controlled release systems, [32][33][34] permselective membranes, 35,36 chromatography media, 37,38 and bilayer membranes. 39,40 However, challenges remain in designing functional membranes based upon ICPs.…”

Section: Introductionmentioning

confidence: 99%

Electrochemically Modulated Permeability of Poly(aniline) and Composite Poly(aniline)−Poly(styrenesulfonate) Membranes

2006

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The influence of oxidation state on the permeability of several probe molecules through conducting polymer membranes comprising composites of poly(aniline) and poly(styrenesulfonate) was examined in aqueous solution. Pure poly(aniline) membranes displayed a characteristic increase in permeability between reduced and half-oxidized states for neutrally charged phenol and negatively charged 4-hydroxybenzenesulfonate. In contrast, positively charged pyridine experienced decreased permeability through the membrane when poly(aniline) was switched from the reduced to the half-oxidized state. This behavior can be explained by a combination of oxidation-induced film swelling and the anion-exchange character of the positively charged membrane. The membrane composition was modified to include a fixed negative charge by the addition of poly(styrenesulfonate) during synthesis. The incorporation of this negatively charged component introduced cation-exchange character to the film and substantially reduced membrane permeability to 4-hydroxybenzenesulfonate in both oxidation states. In addition, increasing the fraction of poly(styrenesulfonate) in the membrane served to decrease film permeability for all species because of a densification of the membrane. This work demonstrates how both film composition and oxidation state can be used to tune the permeability of conducting polymer membranes.

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Retention characteristics of polypyrrole as a stationary phase for the electrochemically modulated liquid chromatographic (EMLC) separations of dansyl amino acids

Cited by 43 publications

References 61 publications

Electrochemically-modulated liquid chromatography (EMLC): Column design, retention processes, and applications

Electrochemically-modulated liquid chromatography (EMLC): Column design, retention processes, and applications

Potential-controlled chromatography for the separation of amino acids and peptides

Electrochemically Modulated Permeability of Poly(aniline) and Composite Poly(aniline)−Poly(styrenesulfonate) Membranes

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