Resveratrol may reverse the effects of long-term occupational exposure to electromagnetic fields on workers of a power plant

Abstract

High-voltage electricity lines are known to generate extremely low-frequency electromagnetic fields (ELF-EMFs). With the process of urbanization, increasing concerns has been focused on the potentially hazardous impacts of ELF-EMF on human health, and the conclusions are controversial. Little is known about the method of prevention against ELF-EMF induced healthy problems. A total of 186 male workers with occupational exposure to high-voltage electricity lines, and 154 male subjects with insignificant exposure as reference control were enrolled in this study. Resveratrol or placebo was given as dietary supplements (500 mg twice daily), and several inflammatory biomarkers and biomarkers of oxidative stress were assessed. Workers who had long-term exposure to high-voltage electricity lines exhibited elevated urinary levels of 8-hydroxy-2-deoxy-guanosine (8-OHdG) and F2-isoprostane, compared to the reference group. Lower plasma nuclear factor kappa B (NF-κB) and interleukin (IL)-6 were observed in exposed workers compared to the reference group. Resveratrol significantly reversed the adverse impacts of ELF-EMF. Stimulated cytokine production by resveratrol was found in exposed workers but not in the reference group. This study supported that occupational and long-term exposure to high-voltage electricity lines has an adverse effect on homeostasis of human body, and resveratrol supplement could be an effective protection strategy against the adverse effects induced by ELF-EMFs.

The use of a bed with an insulating system of electromagnetic fields improves immune function, redox and inflammatory states, and decrease the rate of aging

“…Although there are contradictory results, EMFs largely seem to induce damage in humans [ 20 , 21 , 25 ]. The majority of studies show the relation between EMFs and the risk of many pathologies, especially cancer and neurological diseases, amongst others [ 39 ]. Moreover, exposure to EMFs seems to produce impairment in sleep as well as to generate fatigue and general discomfort [ 40 ].…”

Radioprotective profile of Urtica dioica L. seed extract on oxidative DNA-damage in liver tissue and whole blood of radiation-administered rats

“…Since 8-OHdG was evaluated as a marker for sperm infertility (Hosen et al, 2015), UD extract can be assessed for protection against radiation-induced impact on sperm quality. 8-OHdG was also reported to increase due to electromagnetic fields, which are generated by power plants or conduction cables (Zhang et al, 2017). Therefore, UD extract can also be tested in such models.…”

Effects of Various Densities of 50 Hz Electromagnetic Field on Serum IL-9, IL-10, and TNF-α Levels

“…35 In an in vivo study, lower plasma IL-1β and IL-6 were observed in 186 male workers who had long-term exposure to 5-32 000 Hz EMFs, suggesting that ELF-EMFs may affect the immune system and reduce inflammatory responses. 36 In addition, our previous study indicates that 50 Hz EMFs with a density of 100 µT decreases the rat serum level of IFN-γ, the signature cytokine for the Th1 involved in the pathogenesis of autoimmune disorders. 27 In contrast, Ikdea, et al, report that the levels of TNF-α is not significantly changed in h-PBMCs after a 6-hour exposure to 50 Hz 100-and 500-μT EMFs.…”