Resumption of ovarian function after 4 years of estro-progestin treatment in a young woman with Crohn’s disease and premature ovarian insufficiency: a case report

Abstract

Purpose To report the long-term management of a case of premature ovarian insufficiency of unknown origin in a young woman with Crohn's disease. Method Here is reported the case of a 20 years old woman with Cronh's disease presenting with two years amenorrhea and FSH and LH levels of 255 mIU/ml and 182 mIU/ml respectively, who received 10 months corticosteroid treatment followed by 7 years of estro-progestin treatment.

Premature Ovarian Insufficiency: Past, Present, and Future

“…Primary amenorrhea is more serious than secondary amenorrhea, making reversal easier in the latter. Laboratory test results for FSH, estradiol, and inhibin B can predict the chance of POI reversal ( Caroppo and D’Amato, 2012 ). Oocyte donation is the recommended treatment for infertility due to POI, as it has been proven to achieve a 70–80% successful pregnancy rate, although it may not be available in some countries ( Torrealday et al, 2017 ).…”