Results of screening for retinopathy of prematurity in a large nursery in Kuwait: Incidence and risk factors

Wani, Vivek B; Kumar, Niranjan; Sabti, Khalid Al; Raizada, Seemant; Rashwan, Nabeel; Shukkur, Mumtaz; Harbi, M. N. Al

doi:10.4103/0301-4738.62644

Cited by 27 publications

(35 citation statements)

References 22 publications

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“…However, these improvements have resulted in an increase in the rate of ROP and its severity at presentation 34. These factors have resulted in a steady rise of central visual deficits and birth defects with ROP and cataract as the more common causes of visual deficits and declining rates of infectious and nutritional causes in Group 1 and 2 countries 35. In Group 3 countries, corneal blindness due to Vitamin A deficiencies, infections, and war-related injuries remain the primary etiology of visual deficits 36…”

Section: Causes Of Childhood Blindness and Visual Impairmentmentioning

confidence: 99%

The Status of Childhood Blindness and Functional Low Vision in the Eastern Mediterranean Region in 2012

Khandekar

Kishore

Mansu³

et al. 2014

Middle East Afr J Ophthalmol

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Childhood blindness and visual impairment (CBVI) are major disabilities that compromise the normal development of children. Health resources and practices to prevent CBVI are suboptimal in most countries in the Eastern Mediterranean Region (EMR). We reviewed the magnitude and the etiologies of childhood visual disabilities based on the estimates using socioeconomic proxy indicators such as gross domestic product (GDP) per capita and <5-year mortality rates. The result of these findings will facilitate novel concepts in addressing and developing services to effectively reduce CBVI in this region. The current study determined the rates of bilateral blindness (defined as Best corrected visual acuity(BCVA)) less than 3/60 in the better eye or a visual field of 10° surrounding central fixation) and functional low vision (FLV) (visual impairment for which no treatment or refractive correction can improve the vision up to >6/18 in a better eye) in children <15 years old. We used the 2011 population projections, <5-year mortality rates and GDP per capita of 23 countries (collectively grouped as EMR). Based on the GDP, we divided the countries into three groups; high, middle- and low-income nations. By applying the bilateral blindness and FLV rates to high, middle- and low-income countries from the global literature to the population of children <15 years, we estimated that there could be 238,500 children with bilateral blindness (rate 1.2/1,000) in the region. In addition, there could be approximately 417,725 children with FLV (rate of 2.1/1,000) in the region. The causes of visual disability in the three groups are also discussed based on the available data. As our estimates are based on hospital and blind school studies in the past, they could have serious limitations for projecting the present magnitude and causes of visual disabilities in children of EMR. An effective approach to eye health care and screening for children within primary health care and with the available resources are discussed. The objectives, strategies, and operating procedures for child eye-care are presented. Variables impacting proper screening are discussed. To reach the targets, we recommend urgent implementation of new approaches to low vision and rehabilitation of children.

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Section: Causes Of Childhood Blindness and Visual Impairmentmentioning

confidence: 99%

The Status of Childhood Blindness and Functional Low Vision in the Eastern Mediterranean Region in 2012

Khandekar

Kishore

Mansu³

et al. 2014

Middle East Afr J Ophthalmol

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“…[45614] In our study too, the severe ROP was mainly present in <30 weeks gestation and <1200 g birth weight. All the babies with <1000 g birth were affected (ROP any stage), in our study.…”

Section: Discussionmentioning

confidence: 64%

Retinopathy of prematurity: Risk factors and role of antenatal betamethasone in indian preterm newborn babies

et al. 2014

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Background:Increase in the survival of preterm neonates has led to increased incidence of retinopathy of prematurity (ROP). Among various risk factors, only prematurity is well-established and role of others is still not clear. Effect of antenatal betamethasone on ROP severity is also controversial. Available literature from India has a paucity of information.Objectives:(a) The primary aim of the following study is to find the incidence and risk factors of ROP and (b) secondary aim is to assess the effect of antenatal betamethasone on ROP.Design:prospective, observational cohort study.Setting:Tertiary level neonatal care unit.Materials and Methods:A total of 148 infants ≤ 34 weeks gestation at birth, completed the study protocol. Severe ROP was defined as stage II and higher (including plus disease) of ROP. Various perinatal factors including antenatal betamethasone were analyzed by univariate followed by multivariate analysis.Results:overall incidence of ROP (any stage) was 44.6%. Severe ROP was mainly detected in <1200 g birth weight and/or <30 weeks gestational age. Antenatal betamethasone was associated with non-severe form of ROP (P < 0.05) on univariate analysis, but could not pass multivariate logistic regression analysis. Among other perinatal factors studied, low birth weight (<1200 g) (odds ratio [OR]: 19.699, 95% confidence interval [CI]: 2.42-160.17, P = 0.005), low gestational age (<30 weeks) (OR: 36.52, 95% CI: 3.76-354.3, P = 0.002), acidosis (OR: 6.932, 95% CI: 1.16-41.33, P = 0.034) and blood transfusion (OR: 14.11, 95% CI: 1.494-133.5, P = 0.021) were associated with babies in severe ROP in an independent manner.Conclusions:Low birth weight and low gestational age emerged as independent significant risk factors along with blood transfusion and acidosis. Antenatal betamethasone may be preventive for severe ROP. More studies are however recommended.

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“…5,19 The incidence of ROP requiring laser treatment in present study was 4.5%which was less than some studies in which incidence was 6.7% and 7.8% respectively. 19,20 The ETROP incidence study 3 reported severe pre threshold ROP in 36.9% and 27% incidence of threshold disease was reported in the CRYO ROP study underlining the continued occurrence of this sight-threatening stage of ROP. 21 Some studies have reported incidence less than 5%.…”

Section: Discussionmentioning

confidence: 99%

Retinopathy of prematurity: a study of incidence and risk factors

Parekh¹,

Behera²,

Kulkarni³

et al. 2016

Int J Contemp Pediatr

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Results of screening for retinopathy of prematurity in a large nursery in Kuwait: Incidence and risk factors

Cited by 27 publications

References 22 publications

The Status of Childhood Blindness and Functional Low Vision in the Eastern Mediterranean Region in 2012

The Status of Childhood Blindness and Functional Low Vision in the Eastern Mediterranean Region in 2012

Retinopathy of prematurity: Risk factors and role of antenatal betamethasone in indian preterm newborn babies

Retinopathy of prematurity: a study of incidence and risk factors

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