Results of Long-Term Follow-Up of Patients With Completely Resected Non-Small Cell Lung Cancer

Prognostic factors for cases with no extracranial metastasis in whom brain metastasis is detected after resection of non-small cell lung cancer

“…The most common site of extrathoracic distant metastasis is the brain [1], detecting in approximately 30-55% in an autopsy series of patients with non-small-cell lung cancer (NSCLC) [2]. The prognosis of patients with brain metastasis is poor with a median survival of less than 1 year [3][4][5]. The reason for the poor prognosis of these patients is that brain metastases usually occur late in the course of the disease, often simultaneously with wide-spread systemic metastases [6].…”

Pattern of Imaging after Lung Cancer Resection. 1992–2005

“…Although most recurrences are intrathoracic, up to one-third are extrathoracic recurrences. The latter group is unlikely to benefit from thoracic surveillance imaging (6,(29)(30)(31). Each annual surveillance CT scan adds approximately $1,412 to the cost of additional investigation without affecting outcomes (32).…”

Post-recurrence survival of elderly patients 75 years of age or older with surgically resected non-small cell lung cancer

“…Several studies have demonstrated the outcomes and predictive factors for the post-recurrence survival in resected NSCLC patients [3][4][5][6][7][8][9]. However, few reports have so far evaluated the treatment or outcomes of elderly patients.…”

“…As non-small cell lung cancer (NSCLC) is a common disease in the elderly population, the number of cases of NSCLC is increasing, with patients older than 80 years of age accounting for 14 % of all patients with lung cancer [2]. Although surgery is the best therapeutic modality for patients with early stages of NSCLC, recurrence has been reported to occur in 20-50 % of all cases [3][4][5][6][7][8][9]. According to the Japanese Lung Cancer Registry Study, tumor recurrence remains a major cause of postoperative death [10].…”