Results of a Minimally Invasive Technique for Treatment of Unicameral Bone Cysts

Mik, G; Arkader, Alexandre; Manteghi, Alexander; Dormans, John P.

doi:10.1007/s11999-009-1008-2

Cited by 69 publications

(69 citation statements)

References 28 publications

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“…Although the difference in mean age (8.7 vs 11.3 years) did not reach the level of statistical significance, it was very close to it, so it is probable that younger children are more prone to recurrences [11].…”

Section: Discussionmentioning

confidence: 75%

“…-curettage and bone grafting [7] -injections of steroids, autogenic bone marrow [8], various osteoinductive (demineralised bone matrix [9]) or osteoconductive materials (pastes containing calcium sulphate, calcium hydroxyapatite and tricalcium phosphate [10][11][12]) into the cysts -multiple drilling of the cyst wall [13] -flexible intramedullary nailing [14,15] Curettage and bone grafting were the most common procedures used for the treatment of cysts until the 1980s [7]. A study published by Scaglietti et al reporting that methylprednisolone injections into the cyst resulted in a 96 % treatment success rate was a breakthrough [16].…”

Section: Introductionmentioning

confidence: 99%

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Factors predictive of positive response to steroid therapy in simple bone cysts: an old trick that still works

Flont

Kołacińska-Flont

Niedzielski

2013

International Orthopaedics (SICOT)

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Purpose The aim of the study was to identify clinical, demographic and radiological factors predicting a positive response to steroid treatment in simple bone cysts (SBCs). Methods A retrospective study was conducted on 62 patients. The mean follow-up period was 9.2 years after the final steroid injection. Recurrences were defined according to Neer's scale as modified by Chang et al.. To identify predictive factors, the group of patients who positively responded to treatment (Neer stages I and II, n=39, 62.9 %, group 1) were compared with the group in which recurrences occurred (Nerr stages III and IV, n=23, 37.1 %, group 2). Results Recurrences were experienced by 37

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Section: Discussionmentioning

confidence: 75%

Section: Introductionmentioning

confidence: 99%

Factors predictive of positive response to steroid therapy in simple bone cysts: an old trick that still works

Flont

Kołacińska-Flont

Niedzielski

2013

International Orthopaedics (SICOT)

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“…Treatment can reinforce the bone cortex. Numerous types of treatments have been proposed such as steroids, natural bone marrow, bone matrix or other injection materials [19,24,32,36,42,43], curettage with bone grafting [34], subperiosteal resection [10,23], and internal or external fixation [17,28,31]; however, until now, there was no consensus regarding the best procedure. Moreover, because the various literature reports all methods of treatment with a wide range of healing rates, it is difficult to derive clearcut criteria (Table 5).…”

Section: Volume 468 Number 11 November 2010mentioning

confidence: 99%

Injection of Demineralized Bone Matrix With Bone Marrow Concentrate Improves Healing in Unicameral Bone Cyst

Bella

Dozza

Frisoni

et al. 2010

Clinical Orthopaedics &Amp; Related Research

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Background Unicameral bone cysts are benign lesions that usually spontaneously regress with skeletal maturity; however, the high risk of pathologic fractures often justifies treatment that could reinforce a weakened bone cortex. Various treatments have been proposed but there is no consensus regarding the best procedure. Questions/purposes We compared the healing rates and failures of two methods of cure based on multiple injections of corticosteroid or a single injection of demineralized bone matrix (DBM) in association with bone marrow concentrate (BMC). Methods We retrospectively reviewed 184 patients who had one of the two treatments for unicameral bone cysts with cortical erosion. Clinical records were reviewed for treatment failures and radiographs for healing in all patients. The minimum followup was 12 months for the Steroids Group (mean, 48 months; range, 12-120 months) and 12 months for the DBM + BMC Group (mean, 20 months; range, 12-28 months).Results After one treatment we observed a lower healing rate of cysts treated with multiple injections of steroids compared with the healing after the first injection of DBM + BMC (21% versus 58%, respectively). At last followup, 38% healed with steroids and 71% with DBM + BMC. The rate of failure after one steroid injection was higher than after a single injection of BDM + BMC (63% versus 24%, respectively). We observed no difference in fracture rates after treatment between the two groups.

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“…This technique combines the healing benefits of intramedullary decompression, curettage, and grafting with the lower morbidity of a percutaneous procedure and the decreased donor site morbidity from the use of MGCS pellets [9]. However, regardless of surgical technique, recurrence of UBCs is common [2,9,16].…”

Section: Discussionmentioning

confidence: 99%

Case Report: Unicameral Bone Cysts in a Young Patient with Acquired Generalized Lipodystrophy

Gregory

Arkader

Bothari

et al. 2010

Clinical Orthopaedics &Amp; Related Research

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We report the case of a 13-year-old boy with bilateral distal femoral unicameral bone cysts (UBCs) associated with acquired generalized lipodystrophy. As opposed to congenital generalized lipodystrophy, cystic bone lesions in acquired generalized lipodystrophy are rare. After radiographic and histologic confirmation of the UBCs, we performed percutaneous intramedullary decompression, curettage, and grafting. UBCs can be an important manifestation of acquired generalized lipodystrophy. Cystic bone lesions appear to be less common in acquired generalized lipodystrophy than in congenital generalized lipodystrophy, and intramedullary adipose tissue loss may be a predisposing factor for the development of bone lesions in patients with acquired generalized lipodystrophy. When evaluating a patient with lipodystrophy, doctors should recognize the clinical course may include the development of UBCs.

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Results of a Minimally Invasive Technique for Treatment of Unicameral Bone Cysts

Cited by 69 publications

References 28 publications

Factors predictive of positive response to steroid therapy in simple bone cysts: an old trick that still works

Factors predictive of positive response to steroid therapy in simple bone cysts: an old trick that still works

Injection of Demineralized Bone Matrix With Bone Marrow Concentrate Improves Healing in Unicameral Bone Cyst

Case Report: Unicameral Bone Cysts in a Young Patient with Acquired Generalized Lipodystrophy

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