“…85 In fact, liver disease is currently the main indication for the use of albumin in Spanish ICUs ---its administration in patients with severe sepsis or septic shock being exceptional. 86 There are limitations to the use of albumin, such as the low quality of the evidence on its effectiveness, high cost, and the potential risk of microorganism transmission. 87 Albumin therefore should not be used as resuscitation fluid on a routine basis, though it can be administered in certain groups of patients.…”