Abstract:Restless legs syndrome (RLS) is a frequent complication of hemodialysis that has been associated with poor quality of life and increased risk for complications. Nevertheless, few studies regarding this entity exist in resource-limited settings. Objectives: To determine the prevalence of RLS among Mexican patients on hemodialysis; and compare these patients with a control group of the same population. Methods: We recruited 105 hemodialysis patients. Restless legs syndrome was diagnosed according to the update… Show more
“…RLS causes an overpowering, irresistible need to move legs that is usually due to uncomfortable sensations that exacerbate during periods of inactivity and frequently interfere with the patient's sleep. It is often diagnosed late, especially when the symptoms are mild or nonspecific (Torres, Sifuentes, Teran , Martinez , Luevanos et al 2018). Several factors influence the severity of RLS as; hypertension, diabetes, being female, overweight and obesity, length of dialysis time, and advanced age in patients with hemodialysis.…”
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confidence: 99%
“…The pathophysiology of RLS in patients with chronic kidney disease (CKD) is not well established. Authors have proposed several risk factors but the results of many studies have been inconsistent (Torres, et al 2018) .The underlying cause of RLS, however, remains to be identified. There is some support from neurophysiological studies and neuro imaging that RLS is sub-cortically generated in reticular neuron populations.…”
The patients undergoing hemodialysis usually have several complications including restless leg syndrome, which is a neurological disorder characterized by uncomfortable sensation of paraesthesia in legs that subsequently causes involuntary and continuous movement of the lower limbs especially in night which can lead to; sleep disorder, anxiety, fatigue, depression, disturbance of ability to work and social isolation. Moderate exercise may be helpful in relieving restless leg syndrome. The aim of the study is to assess the effect of muscles stretching exercises on severity of restless legs syndrome of adult patients undergoing hemodialysis. A quasi-experimental design was utilized. Sample: 40 convenience adult patients diagnosed with renal failure and undergoing hemodialysis. Settings; Hemodialysis department in the Students Hospital Affiliated to Tanta University and Elmabra Hospital for Health Insurance. Data collection: Structured interview used to elicit data which comprises two tools; Tool 1: Health assessment tool which include Bio-Socio-demographic characteristics data; Tool 2: International Restless Legs Syndrome Rating Scale (IRLSRS). Data was collected through three phases; Assessment, implementation and evaluation phase through 20 weeks. Results: Indicated improvement of severity of restless leg syndrome symptoms of the study group post comparing to pre muscle stretching exercise. Conclusion: muscles stretching exercise plays an important role in reducing the severity of RLS symptoms of adult patients undergoing hemodialysis. Recommendation: Nurses has to be encouraged to help alleviate the severity of RLS symptoms by training muscle stretching exercises to the patients undergoing heamodialysis.
“…RLS causes an overpowering, irresistible need to move legs that is usually due to uncomfortable sensations that exacerbate during periods of inactivity and frequently interfere with the patient's sleep. It is often diagnosed late, especially when the symptoms are mild or nonspecific (Torres, Sifuentes, Teran , Martinez , Luevanos et al 2018). Several factors influence the severity of RLS as; hypertension, diabetes, being female, overweight and obesity, length of dialysis time, and advanced age in patients with hemodialysis.…”
mentioning
confidence: 99%
“…The pathophysiology of RLS in patients with chronic kidney disease (CKD) is not well established. Authors have proposed several risk factors but the results of many studies have been inconsistent (Torres, et al 2018) .The underlying cause of RLS, however, remains to be identified. There is some support from neurophysiological studies and neuro imaging that RLS is sub-cortically generated in reticular neuron populations.…”
The patients undergoing hemodialysis usually have several complications including restless leg syndrome, which is a neurological disorder characterized by uncomfortable sensation of paraesthesia in legs that subsequently causes involuntary and continuous movement of the lower limbs especially in night which can lead to; sleep disorder, anxiety, fatigue, depression, disturbance of ability to work and social isolation. Moderate exercise may be helpful in relieving restless leg syndrome. The aim of the study is to assess the effect of muscles stretching exercises on severity of restless legs syndrome of adult patients undergoing hemodialysis. A quasi-experimental design was utilized. Sample: 40 convenience adult patients diagnosed with renal failure and undergoing hemodialysis. Settings; Hemodialysis department in the Students Hospital Affiliated to Tanta University and Elmabra Hospital for Health Insurance. Data collection: Structured interview used to elicit data which comprises two tools; Tool 1: Health assessment tool which include Bio-Socio-demographic characteristics data; Tool 2: International Restless Legs Syndrome Rating Scale (IRLSRS). Data was collected through three phases; Assessment, implementation and evaluation phase through 20 weeks. Results: Indicated improvement of severity of restless leg syndrome symptoms of the study group post comparing to pre muscle stretching exercise. Conclusion: muscles stretching exercise plays an important role in reducing the severity of RLS symptoms of adult patients undergoing hemodialysis. Recommendation: Nurses has to be encouraged to help alleviate the severity of RLS symptoms by training muscle stretching exercises to the patients undergoing heamodialysis.
“…In CKD-aP, statistically significant associations were found amongst itching severity and health-related quality-of-life domains such as mood, social relations, and sleep [10]. Those with CKD-aP may also be more likely to suffer restless leg syndrome [11]. In addition, patients with severe CKD-aP have a significantly worse prognosis than patients with less severe CKD-aP, with severe CKD-aP being independently associated with mortality even after adjusting for other clinical factors including diabetes mellitus, age, β2-microglobulin, and albumin [12].…”
Section: Clinical Characteristics and Natural Historymentioning
<b><i>Background:</i></b> Chronic kidney disease-associated pruritus (CKD-aP), also known as uraemic pruritus, is a disabling symptom for patients and a challenging condition for clinicians. Despite being common amongst end-stage kidney disease (ESKD) patients, it remains underestimated and underdiagnosed. The exact pathogenesis remains largely elusive, which hampers the synthesis of a definite treatment approach. <b><i>Summary:</i></b> Chronic pruritus (lasting 6 weeks or more in duration) is a common and potentially disabling symptom in patients with advanced CKD. A unified hypothesis of pathogenesis has not yet been concluded. Studies have shown changes in the immunochemical milieu of the skin in patients with CKD-aP with several inciting stimuli identified. However, other unrecognized factors are likely to be involved. This article will review the current observations and understanding of the postulated pathogenesis of CKD-aP, as well as the evidence for current management strategies. <b><i>Key Messages:</i></b> CKD-aP is a common and troubling symptom amongst ESKD patients that is associated with decreased quality of life and poor prognosis. Its exact pathogenesis, at the time of writing, is not well-understood. A stepwise approach is recommended for management. Systematic reviews show the largest body of evidence was found for the effectiveness of gabapentin. Comparison is needed between newly emerging pharmacological agents such as kappa-opioid receptor agonists and more established agents, such as the gabapentinoids. Finally, renal transplantation should be considered in severe and refractory cases who are suitable transplant candidates as it has shown an excellent outcome in most cases.
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