2005
DOI: 10.1590/s0102-09352005000100007
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Abstract: Resposta da paratireóide de ratas às variações do cálcio e fósforo plasmáticos no hipertireoidismo e hipogonadismo RESUMOForam estudadas 84 paratireóides de ratas Wistar com cinco meses de idade, castradas ou não, e mantidas em hipertireoidismo por períodos de 30, 60 e 90 dias. Dois grupos eutireóideos, um castrado e o outro não, foram mantidos nas mesmas condições e serviram de controle. Ao final de cada período, foram colhidos o plasma, para determinação da concentração de T4 livre, o cálcio e o fósforo e as… Show more

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Cited by 2 publications
(3 citation statements)
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References 11 publications
(9 reference statements)
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“…Serakides et al (2005) obtained positive result of hyperthyroid induction in rats after administering 50 g of Lthyroxin/animal/day, for 30 days. This dosage for mice is likely to lead to an intoxication status, as it is a synthetic hormone and its action in the organism is dose-dependent.…”
Section: Resultsmentioning
confidence: 90%
See 1 more Smart Citation
“…Serakides et al (2005) obtained positive result of hyperthyroid induction in rats after administering 50 g of Lthyroxin/animal/day, for 30 days. This dosage for mice is likely to lead to an intoxication status, as it is a synthetic hormone and its action in the organism is dose-dependent.…”
Section: Resultsmentioning
confidence: 90%
“…Experimental studies associated with thyroid dysfunctions and changes in the metabolism and body development are based on the suppression of hormone production (McCardle et al, 1998;Ferreira et al, 2003;Khotimchenko e Sergushchenko, 2003;Silva et al, 2004) or thyroxin administration in high doses promoting an iatrogenic hyperthyroidism status (Kobayashi et al, 2000;Serakides et al, 2002;2005). However, most studies recommend the use of traumatic methods and protocols, as for hormone dosage or the induction methodology using rats as animal model.…”
Section: Introductionmentioning
confidence: 99%
“…Serakides et al (2005), em um estudo com 108 ratas com deficiência hormonal mantidas em hipertireoidismo por períodos de 30, 60 e 90 dias, observou que a ovariectomia isoladamente elevou os níveis plasmáticos de fosfato e tiroxina livre.…”
Section: Parâmetros Bioquímicosunclassified